Inflammatory mechanisms contributing to endothelial dysfunction
Maintenance of endothelial cell integrity is an important component of human health and
disease since the endothelium can perform various functions including regulation of …
disease since the endothelium can perform various functions including regulation of …
[HTML][HTML] Type 2 diabetes mellitus, oxidative stress and inflammation: examining the links
OO Oguntibeju - International journal of physiology …, 2019 - ncbi.nlm.nih.gov
Diabetes mellitus has been recognised as one of the four major non-communicable
diseases that demands urgent attention from all key shareholders globally in an effort to …
diseases that demands urgent attention from all key shareholders globally in an effort to …
Oxidative stress in type 2 diabetes: impacts from pathogenesis to lifestyle modifications
Oxidative stress is a critical factor in the pathogenesis and progression of diabetes and its
associated complications. The imbalance between reactive oxygen species (ROS) …
associated complications. The imbalance between reactive oxygen species (ROS) …
New therapeutic implications of endothelial nitric oxide synthase (eNOS) function/dysfunction in cardiovascular disease
The Global Burden of Disease Study identified cardiovascular risk factors as leading causes
of global deaths and life years lost. Endothelial dysfunction represents a pathomechanism …
of global deaths and life years lost. Endothelial dysfunction represents a pathomechanism …
[HTML][HTML] Mitochondria and cardiovascular diseases—from pathophysiology to treatment
Mitochondria are the source of cellular energy production and are present in different types
of cells. However, their function is especially important for the heart due to the high demands …
of cells. However, their function is especially important for the heart due to the high demands …
[PDF][PDF] The role of Nrf2 in oxidative stress-induced endothelial injuries
B Chen, Y Lu, Y Chen, J Cheng - J Endocrinol, 2015 - scholar.archive.org
Endothelial dysfunction is an important risk factor for cardiovascular disease, and it
represents the initial step in the pathogenesis of atherosclerosis. Failure to protect against …
represents the initial step in the pathogenesis of atherosclerosis. Failure to protect against …
The function of Rho-associated kinases ROCK1 and ROCK2 in the pathogenesis of cardiovascular disease
S Hartmann, AJ Ridley, S Lutz - Frontiers in pharmacology, 2015 - frontiersin.org
Rho-associated kinases ROCK1 and ROCK2 are serine/threonine kinases that are
downstream targets of the small GTPases RhoA, RhoB, and RhoC. ROCKs are involved in …
downstream targets of the small GTPases RhoA, RhoB, and RhoC. ROCKs are involved in …
The role of Nrf2 in cardiovascular function and disease
Free radicals, reactive oxygen/nitrogen species (ROS/RNS), hydrogen sulphide, and
hydrogen peroxide play an important role in both intracellular and intercellular signaling; …
hydrogen peroxide play an important role in both intracellular and intercellular signaling; …
Non-alcoholic fatty liver disease and risk of cardiovascular disease
Non-alcoholic fatty liver disease (NAFLD) has become the leading cause of chronic liver
diseases worldwide, causing considerable liver-related mortality and morbidity. During the …
diseases worldwide, causing considerable liver-related mortality and morbidity. During the …
The anti-inflammatory effects of statins on coronary artery disease: an updated review of the literature
E Diamantis, G Kyriakos… - Current cardiology …, 2017 - ingentaconnect.com
Background: Statins have long been used for the protection against coronary artery disease
(CAD). Their beneficial effect apart from cholesterol reduction lies in their pleiotropic …
(CAD). Their beneficial effect apart from cholesterol reduction lies in their pleiotropic …