Breast cancer incidence and mortality rates have been consistently high among women. The
use of diverse therapeutic strategies, including chemotherapy, endocrine therapy, targeted …

Breast cancer remains the most common malignant cancer in women, with a staggering
incidence of two million cases annually worldwide; therefore, it is crucial to explore novel …

Triple-negative breast cancer (TNBC) is associated with an elevated risk of recurrence and
poor prognosis. Historically, only chemotherapy was available as systemic treatment, but …

Cancer-associated fibroblasts (CAFs) are key actors in regulating cancer progression. They
promote tumor growth, metastasis formation, and induce drug resistance. For these reasons …

Chemotherapy is a mainstream cancer treatment, but has a constant challenge of drug
resistance, which consequently leads to poor prognosis in cancer treatment. For better …

Breast cancer is a complex disease that is influenced by the concurrent influence of multiple
genetic and environmental factors. Recent advances in genomics and other high throughput …

A typical genome-wide association study (GWAS) analyzes millions of single-nucleotide
polymorphisms (SNPs), several of which are in a region of the same gene. To conduct gene …

The 3D multicellular tumor spheroid (MTS) model exhibits enhanced fidelity in replicating
the tumor microenvironment and demonstrates exceptional resistance to clinical drugs …

Recent advances in sample preparation and sequencing technology have made it possible
to profile the transcriptomes of individual cells using single-cell RNA sequencing (scRNA …

Acute lymphoblastic leukemia (ALL) is a disease of lymphocyte origin predominantly
diagnosed in children. While its 5-year survival rate is high, resistance to chemotherapy …