Cancer stem cells (CSCs), a small subset of cells in tumors that are characterized by self-
renewal and continuous proliferation, lead to tumorigenesis, metastasis, and maintain tumor …

Macrophages infiltrating tumour tissues or residing in the microenvironment of solid tumours
are known as tumour-associated macrophages (TAMs). These specialized immune cells …

Cancer stem cells (CSCs) are self-renewing cells that facilitate tumor initiation, promote
metastasis, and enhance cancer therapy resistance. Transcriptomic analyses across many …

Cancer progression is primarily caused by interactions between transformed cells and the
components of the tumor microenvironment (TME). TAMs (tumor-associated macrophages) …

Cancer stem cells (CSCs) play an important role during metastasis, but the dynamic
behavior and induction mechanisms of CSCs are not well understood. Here, we employ …

Our previous studies have showed that CC motif chemokine ligand 20 (CCL20) advanced
tumor progression and enhanced the chemoresistance of cancer cells by positively …

Elimination of cancer stem cells (CSCs) and reinvigoration of antitumor immunity remain
unmet challenges for cancer therapy. Tumor-associated macrophages (TAMs) constitute the …

Tumor-associated macrophages (TAMs) play a pivotal role in the progression and
resistance of tumors to different anticancer drugs. TAMs can modulate the tumor …

Myeloid cells infiltrating tumors are gaining ever growing attention in the last years because
their pro-tumor and immunosuppressive functions are relevant for disease progression and …

Tumors consist of heterogeneous cell populations, and tumor heterogeneity plays key roles
in regulating tumorigenesis, metastasis, recurrence and resistance to anti-tumor therapies …