Consensus recommendations for an integrated diagnostic approach to peripheral nerve sheath tumors arising in the setting of Neurofibromatosis Type 1
Consensus recommendations published in 2017 histologically defining atypical
neurofibromatous neoplasm of uncertain biologic potential (ANNUBP) and malignant …
neurofibromatous neoplasm of uncertain biologic potential (ANNUBP) and malignant …
[HTML][HTML] A Sequencing Overview of Malignant Peripheral Nerve Sheath Tumors: Findings and Implications for Treatment
Malignant peripheral nerve sheath tumors (MPNSTs) are rare but aggressive malignancies
with a low 5-year survival rate despite current treatments. MPNSTs frequently harbor …
with a low 5-year survival rate despite current treatments. MPNSTs frequently harbor …
Past, Present, and Future Therapeutic Strategies for NF-1-Associated Tumors
Abstract Purpose of Review Neurofibromatosis type 1 (NF-1) is a cancer predisposition
syndrome caused by mutations in the NF1 tumor suppressor gene that encodes the …
syndrome caused by mutations in the NF1 tumor suppressor gene that encodes the …
[HTML][HTML] Proof of Concept for Genome Profiling of the Neurofibroma/Sarcoma Sequence in Neurofibromatosis Type 1
IR Cannizzaro, M Treccani, A Taiani… - International Journal of …, 2024 - mdpi.com
Neurofibromatosis type 1 (NF1) is an autosomal dominant genetic disorder characterized by
the predisposition to develop tumors such as malignant peripheral nerve sheath tumors …
the predisposition to develop tumors such as malignant peripheral nerve sheath tumors …
Disproportionate adverse event signals of selumetinib in neurofibromatosis type I: insights from FAERS
L Li - Frontiers in Pharmacology, 2025 - frontiersin.org
Background Neurofibromatosis type 1 (NF1) is a rare neurogenetic disorder with limited
treatment options. Selumetinib, a MEK1/2 inhibitor, has emerged as a promising therapy for …
treatment options. Selumetinib, a MEK1/2 inhibitor, has emerged as a promising therapy for …
[HTML][HTML] Basic Research Advances and Challenges in NF1 and NF2 Related Pediatric Tumors
Q Dai, X Zhai, J Huang - 2024 - intechopen.com
This chapter provides a comprehensive overview of the research progress and challenges
in neurofibromatosis type 1 (NF1) and neurofibromatosis type 2 (NF2), with a focus on …
in neurofibromatosis type 1 (NF1) and neurofibromatosis type 2 (NF2), with a focus on …