Microbial consortia have been used in biotechnology processes, including fermentation,
waste treatment, and agriculture, for millennia. Today, synthetic biologists are increasingly …

Building an artificial cell is a research area that is rigorously studied in the field of synthetic
biology. It has brought about much attention with the aim of ultimately constructing a natural …

Communities of microbes play important roles in natural environments and hold great
potential for deploying division-of-labor strategies in synthetic biology and bioproduction …

Synthetic microbial consortia represent a new frontier for synthetic biology given that they
can solve more complex problems than monocultures. However, most attempts to co …

Cell-free systems offer a promising approach to engineer biology since their open nature
allows for well-controlled and characterized reaction conditions. In this review, we discuss …

We demonstrate a simple, robust, and low-cost method for producing the PURE cell-free
transcription–translation system. Our OnePot PURE system achieved a protein synthesis …

Building a live cell from non‐living building blocks would be a fundamental breakthrough in
biological sciences, and it would enable engineering new lineages of life, not directly …

The ability to identify single-nucleotide mutations is critical for probing cell biology and for
precise detection of disease. However, the small differences in hybridization energy …

Hands-on demonstrations greatly enhance the teaching of science, technology,
engineering, and mathematics (STEM) concepts and foster engagement and exploration in …

Cell-free gene expression (CFE) systems empower synthetic biologists to build biological
molecules and processes outside of living intact cells. The foundational principle is that …