Adaptive immunity is mediated by T‐and B‐cells, which are immune cells capable of
develo** pathogen‐specific memory that confers immunological protection. Memory and …

Throughout the body, T cells monitor MHC-bound ligands expressed on the surface of
essentially all cell types. MHC ligands that trigger a T cell immune response are referred to …

Detection of somatic mutations in human leukocyte antigen (HLA) genes using whole-
exome sequencing (WES) is hampered by the high polymorphism of the HLA loci, which …

IMA901 is the first therapeutic vaccine for renal cell cancer (RCC) consisting of multiple
tumor-associated peptides (TUMAPs) confirmed to be naturally presented in human cancer …

Purpose: The majority of tumor-specific antigens are intracellular and/or secreted and
therefore inaccessible by conventional chimeric antigen receptor (CAR) T-cell therapy …

Background Knowledge about and identification of T cell tumor antigens may inform the
development of T cell receptor-engineered adoptive cell transfer or personalized cancer …

The advent in recent years of the application of tetrameric arrays of class I peptide–MHC
complexes now enables us to detect and study rare populations of antigen‐specific CD8+ T …

Mesoporous silica molecular sieves have been prepared by the hydrolysis of
tetraethylorthosilicate in the presence of low-cost, nontoxic, and biodegradable polyethylene …

The purpose of this article is to provide a compendium of major histocompatibility complex
(MHC) peptide motifs and MHC ligands known to date, together with a discussion of the …

A mutated cyclin-dependent kinase 4 (CDK4) was identified as a tumor-specific antigen
recognized by HLA-A2. 1-restricted autologous cytolytic T lymphocytes (CTLs) in a human …