Nanoparticle drug delivery systems and their applications as targeted therapies for triple negative breast cancer

X Kong, Y Qi, X Wang, R Jiang, J Wang, Y Fang… - Progress in Materials …, 2023 - Elsevier
The therapeutic effect of highly malignant triple negative breast cancer (TNBC) is negatively
affected by the formation of tumor cell resistant clone and the severe toxicity of …

Gathering brings strength: How organic aggregates boost disease phototheranostics

J Qi, H Ou, Q Liu, D Ding - Aggregate, 2021 - Wiley Online Library
Phototheranostics that concurrently and complementarily integrate real‐time diagnosis and
in situ therapeutic capabilities in one platform has become the advancing edge of precision …

Mussel-inspired chemistry: a promising strategy for natural polysaccharides in biomedical applications

F Liu, X Liu, F Chen, Q Fu - Progress in Polymer Science, 2021 - Elsevier
Polysaccharides are a kind of natural biopolymers and have been widely applied in various
fields, especially biomedical applications, due to their fascinating properties, such as …

Small‐molecule prodrug nanoassemblies: an emerging nanoplatform for anticancer drug delivery

G Li, B Sun, Y Li, C Luo, Z He, J Sun - Small, 2021 - Wiley Online Library
The antitumor efficiency and clinical translation of traditional nanomedicines is mainly
restricted by low drug loading, complex preparation technology, and potential toxicity …

[HTML][HTML] Carrier-free nanodrugs with efficient drug delivery and release for cancer therapy: From intrinsic physicochemical properties to external modification

H Mei, S Cai, D Huang, H Gao, J Cao, B He - Bioactive materials, 2022 - Elsevier
The considerable development of carrier-free nanodrugs has been achieved due to their
high drug-loading capability, simple preparation method, and offering “all-in-one” functional …

Rational design of a minimalist nanoplatform to maximize immunotherapeutic efficacy: Four birds with one stone

S Zhou, Q Shang, N Wang, Q Li, A Song… - Journal of Controlled …, 2020 - Elsevier
Chemotherapy sometimes can cause potential tumor-specific T-cell-mediated immune
response via stimulating immunogenic cell death (ICD). However, such immune response is …

Self-delivery photo-immune stimulators for photodynamic sensitized tumor immunotherapy

LP Zhao, RR Zheng, JQ Huang, XY Chen, FA Deng… - ACS …, 2020 - ACS Publications
Self-delivery of photosensitizer and immune modulator to tumor site is highly
recommendable to improve the photodynamic immunotherapy yet remains challenging …

Self-Delivery Nanomedicine for O2-Economized Photodynamic Tumor Therapy

LP Zhao, RR Zheng, HQ Chen, LS Liu, XY Zhao… - Nano Letters, 2020 - ACS Publications
Tumor hypoxia is the Achilles heel of oxygen-dependent photodynamic therapy (PDT), and
tremendous challenges are confronted to reverse the tumor hypoxia. In this work, an …

Ferroptosis: The entanglement between traditional drugs and nanodrugs in tumor therapy

K Liu, L Huang, S Qi, S Liu, W **e, L Du… - Advanced …, 2023 - Wiley Online Library
Ferroptosis is a non‐apoptotic programmed cell death caused by the accumulation of lipid
peroxide. System Xc‐/glutathione peroxidase 4 (GPX4) axis and iron axis are two main …

Delivering more for less: nanosized, minimal-carrier and pharmacoactive drug delivery systems

EL Etter, KC Mei, J Nguyen - Advanced drug delivery reviews, 2021 - Elsevier
Traditional nanoparticle carriers such as liposomes, micelles, and polymeric vehicles
improve drug delivery by protecting, stabilizing, and increasing the circulatory half-life of the …