[HTML][HTML] NanoSIMS for biological applications: current practices and analyses

J Nuñez, R Renslow, JB Cliff, CR Anderton - Biointerphases, 2018 - pubs.aip.org
Secondary ion mass spectrometry (SIMS) has become an increasingly utilized tool in
biologically relevant studies. Of these, high lateral resolution methodologies using the …

Oxidative stress: a suitable therapeutic target for optic nerve diseases?

F Buonfiglio, EW Böhm, N Pfeiffer, A Gericke - Antioxidants, 2023 - mdpi.com
Optic nerve disorders encompass a wide spectrum of conditions characterized by the loss of
retinal ganglion cells (RGCs) and subsequent degeneration of the optic nerve. The etiology …

Role of oxidative stress in ocular diseases associated with retinal ganglion cells degeneration

EYC Kang, PK Liu, YT Wen, PMJ Quinn, SR Levi… - Antioxidants, 2021 - mdpi.com
Ocular diseases associated with retinal ganglion cell (RGC) degeneration is the most
common neurodegenerative disorder that causes irreversible blindness worldwide. It is …

[HTML][HTML] Restoring the oxidative balance in age-related diseases–An approach in glaucoma

PR Cáceres-Vélez, F Hui, J Hercus, B Bui… - Ageing Research …, 2022 - Elsevier
As human life expectancy increases, age-related health issues including neurodegenerative
diseases continue to rise. Regardless of genetic or environmental factors, many …

Lycium Barbarum (Wolfberry) Reduces Secondary Degeneration and Oxidative Stress, and Inhibits JNK Pathway in Retina after Partial Optic Nerve Transection

H Li, Y Liang, K Chiu, Q Yuan, B Lin, RCC Chang… - PLoS …, 2013 - journals.plos.org
Our group has shown that the polysaccharides extracted from Lycium barbarum (LBP) are
neuroprotective for retinal ganglion cells (RGCs) in different animal models. Protecting …

Mechanisms of secondary degeneration after partial optic nerve transection

HY Li, YW Ruan, CR Ren, Q Cui… - Neural regeneration …, 2014 - journals.lww.com
Secondary degeneration occurs commonly in the central nervous system after traumatic
injuries and following acute and chronic diseases, including glaucoma. A constellation of …

Topical recombinant human Nerve growth factor (rh-NGF) is neuroprotective to retinal ganglion cells by targeting secondary degeneration

L Guo, BM Davis, N Ravindran, J Galvao, N Kapoor… - Scientific reports, 2020 - nature.com
Optic neuropathy is a major cause of irreversible blindness worldwide, and no effective
treatment is currently available. Secondary degeneration is believed to be the major …

Differential effects of 670 and 830 nm red near infrared irradiation therapy: a comparative study of optic nerve injury, retinal degeneration, traumatic brain and spinal …

MK Giacci, L Wheeler, S Lovett, E Dishington, B Majda… - PloS one, 2014 - journals.plos.org
Red/near-infrared irradiation therapy (R/NIR-IT) delivered by laser or light-emitting diode
(LED) has improved functional outcomes in a range of CNS injuries. However, translation of …

Tunable alginate hydrogels as injectable drug delivery vehicles for optic neuropathy

CJ Maxwell, AM Soltisz, WW Rich… - … Research Part A, 2022 - Wiley Online Library
Many disease pathologies, particularly in the eye, are induced by oxidative stress. In
particular, injury to the optic nerve (ON), or optic neuropathy, is one of the most common …

Damage mechanisms to oligodendrocytes and white matter in central nervous system injury: the Australian context

A Warnock, LM Toomey, AJ Wright, K Fisher… - Journal of …, 2020 - liebertpub.com
Traumatic brain injury (TBI) and spinal cord injury (SCI) present a significant contribution to
the global disease burden. White matter tracts are susceptible to both the physical forces of …