Accelerating the characterization of dynamic DNA origami devices with deep neural networks

Y Wang, X **, C Castro - Scientific Reports, 2023 - nature.com
Mechanical characterization of dynamic DNA nanodevices is essential to facilitate their use
in applications like molecular diagnostics, force sensing, and nanorobotics that rely on …

Optimizing Binding among Bimolecular Tethered Complexes

K Pekar, RT Young, S Sensale - The Journal of Physical Chemistry …, 2024 - ACS Publications
Tethered motion is ubiquitous in nature, offering controlled movement and spatial
constraints to otherwise chaotic systems. The enhanced functionality and practical utility of …

A mean-field theory for characterizing the closing rates of DNA origami hinges

IO Yeboah, RT Young, M Mosioma… - The Journal of Chemical …, 2024 - pubs.aip.org
The evolution of dynamic DNA nanostructures has propelled DNA nanotechnology into a
robust and versatile field, offering groundbreaking applications in nanoscale …

Realizing Mechanical Frustration at the Nanoscale Using DNA Origami

AS Madhvacharyula, R Li, AA Swett, Y Du, FC Simmel… - bioRxiv, 2024 - biorxiv.org
Structural designs inspired by physical and biological systems have been previously utilized
to develop advanced mechanical metamaterials. These are based on the clever geometric …