Microtubules are polarized cytoskeletal filaments that serve as tracks for intracellular
transport and form a scaffold that positions organelles and other cellular components and …

Cell invasion into the surrounding extracellular matrix or across tissue boundaries and
endothelial barriers occurs in both physiological and pathological scenarios such as …

Microtubules control cell architecture by serving as a scaffold for intracellular transport,
signaling, and organelle positioning. Microtubules are intrinsically polarized, and their …

Cell adhesion to the extracellular matrix is essential for cellular processes, such as migration
and invasion. In response to cues from the microenvironment, integrin-mediated adhesions …

The lymph node (LN) is the primary site of alloimmunity activation and regulation during
transplantation. Here, we investigated how fibroblastic reticular cells (FRCs) facilitate the …

Lymph nodes (LNs) act as filters, constantly sampling peripheral cues. This is facilitated by
the conduit network, a tubular structure of aligned extracellular matrix (ECM) fibrils …

The intracellular coral–dinoflagellate symbiosis is the engine that underpins the success of
coral reefs, one of the most diverse ecosystems on the planet. However, the breakdown of …

Microtubule organization in cells relies on targeting mechanisms. Cytoplasmic linker
proteins (CLIPs) and CLIP-associated proteins (CLASPs) are key regulators of microtubule …

Integrin adhesion complexes (IACs) bridge the extracellular matrix to the actin cytoskeleton
and transduce signals in response to both chemical and mechanical cues. The composition …

Integrins are transmembrane receptors that transduce biochemical and mechanical signals
across the plasma membrane and promote cell adhesion and migration. In addition, integrin …