Obesity phenotypes, diabetes, and cardiovascular diseases
This review addresses the interplay between obesity, type 2 diabetes mellitus, and
cardiovascular diseases. It is proposed that obesity, generally defined by an excess of body …
cardiovascular diseases. It is proposed that obesity, generally defined by an excess of body …
Metabolism and metabolic disorders and the microbiome: the intestinal microbiota associated with obesity, lipid metabolism, and metabolic health—pathophysiology …
J Aron-Wisnewsky, MV Warmbrunn, M Nieuwdorp… - Gastroenterology, 2021 - Elsevier
Changes in the intestinal microbiome have been associated with obesity and type 2
diabetes, in epidemiological studies and studies of the effects of fecal transfer in germ-free …
diabetes, in epidemiological studies and studies of the effects of fecal transfer in germ-free …
Imbalanced gut microbiota fuels hepatocellular carcinoma development by sha** the hepatic inflammatory microenvironment
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths worldwide,
and therapeutic options for advanced HCC are limited. Here, we observe that intestinal …
and therapeutic options for advanced HCC are limited. Here, we observe that intestinal …
Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women
Hepatic steatosis is a multifactorial condition that is often observed in obese patients and is
a prelude to non-alcoholic fatty liver disease. Here, we combine shotgun sequencing of fecal …
a prelude to non-alcoholic fatty liver disease. Here, we combine shotgun sequencing of fecal …
Gut microbiome, intestinal permeability, and tissue bacteria in metabolic disease: perpetrators or bystanders?
The emerging evidence on the interconnectedness between the gut microbiome and host
metabolism has led to a paradigm shift in the study of metabolic diseases such as obesity …
metabolism has led to a paradigm shift in the study of metabolic diseases such as obesity …
Inherent bacterial DNA contamination of extraction and sequencing reagents may affect interpretation of microbiota in low bacterial biomass samples
A Glassing, SE Dowd, S Galandiuk, B Davis… - Gut pathogens, 2016 - Springer
Background The advent and use of highly sensitive molecular biology techniques to explore
the microbiota and microbiome in environmental and tissue samples have detected the …
the microbiota and microbiome in environmental and tissue samples have detected the …
Metagenomic profiling pipelines improve taxonomic classification for 16S amplicon sequencing data
Most experiments studying bacterial microbiomes rely on the PCR amplification of all or part
of the gene for the 16S rRNA subunit, which serves as a biomarker for identifying and …
of the gene for the 16S rRNA subunit, which serves as a biomarker for identifying and …
Role of the gut microbiota in host appetite control: bacterial growth to animal feeding behaviour
SO Fetissov - Nature Reviews Endocrinology, 2017 - nature.com
The life of all animals is dominated by alternating feelings of hunger and satiety—the main
involuntary motivations for feeding-related behaviour. Gut bacteria depend fully on their host …
involuntary motivations for feeding-related behaviour. Gut bacteria depend fully on their host …
Type 2 diabetes influences bacterial tissue compartmentalisation in human obesity
Visceral obesity is a key risk factor for type 2 diabetes (T2D). Whereas gut dysbiosis appears
to be instrumental for this relationship, whether gut-associated signatures translocate to …
to be instrumental for this relationship, whether gut-associated signatures translocate to …
Comprehensive description of blood microbiome from healthy donors assessed by 16 S targeted metagenomic sequencing
S Païssé, C Valle, F Servant, M Courtney… - …, 2016 - Wiley Online Library
BACKGROUND Recent studies have revealed that the blood of healthy humans is not as
sterile as previously supposed. The objective of this study was to provide a comprehensive …
sterile as previously supposed. The objective of this study was to provide a comprehensive …