Energy-representation theory of solutions: Its formulation and application to soft, molecular aggregates

N Matubayasi - Bulletin of the Chemical Society of Japan, 2019 - academic.oup.com
The energy-representation theory of solutions is developed to address the dissolution of a
molecule in homogeneous fluid as well as the partitioning into such nanoscale structures as …

Free-energy decomposition of salt effects on the solubilities of small molecules and the role of excluded-volume effects

S Hervø-Hansen, D Lin, K Kasahara… - Chemical Science, 2024 - pubs.rsc.org
The roles of cations and anions are different in the perturbation on solvation, and thus, the
analyses of the separated contributions from cations and anions are useful to establish …

Total free energy analysis of fully hydrated proteins

J Kalayan, A Chakravorty, J Warwicker… - Proteins: Structure …, 2023 - Wiley Online Library
The total free energy of a hydrated biomolecule and its corresponding decomposition of
energy and entropy provides detailed information about regions of thermodynamic stability …

Thermodynamic decomposition of solvation free energies with particle mesh Ewald and long-range Lennard-Jones interactions in Grid Inhomogeneous Solvation …

L Chen, A Cruz, DR Roe, AC Simmonett… - Journal of chemical …, 2021 - ACS Publications
Grid Inhomogeneous Solvation Theory (GIST) maps out solvation thermodynamic properties
on a fine meshed grid and provides a statistical mechanical formalism for thermodynamic …

Short solvent model for ion correlations and hydrophobic association

A Gao, RC Remsing, JD Weeks - Proceedings of the …, 2020 - National Acad Sciences
Coulomb interactions play a major role in determining the thermodynamics, structure, and
dynamics of condensed-phase systems, but often present significant challenges. Computer …

Noncovalent sulfoxide–nitrile coupling involving four-center heteroleptic dipole–dipole interactions between the sulfinyl and nitrile groups

DM Ivanov, SV Baykov, AS Novikov… - Crystal Growth & …, 2020 - ACS Publications
The 4-X-5-nitro substituted phthalodinitriles (X= Br 1, I 2) were crystallized from Me2SO
solutions affording crystalline adducts (1–2)· Me2SO, which were characterized by X-ray …

Free Energy Density of a Fluid and Its Role in Solvation and Binding

MK Gilson, T Kurtzman - Journal of Chemical Theory and …, 2024 - ACS Publications
The concept that a fluid has a position-dependent free energy density appears in the
literature but has not been fully developed or accepted. We set this concept on an …

Anion–cation contrast of small molecule solvation in salt solutions

S Hervø-Hansen, J Heyda, M Lund… - Physical Chemistry …, 2022 - pubs.rsc.org
The contributions from anions and cations from salt are inseparable in their perturbation of
molecular systems by experimental and computational methods, rendering it difficult to …

Role of displacing confined solvent in the conformational equilibrium of β-cyclodextrin

P He, S Sarkar, E Gallicchio, T Kurtzman… - The Journal of …, 2019 - ACS Publications
This study investigates the role of hydration and its relationship to the conformational
equilibrium of the host molecule β-cyclodextrin. Molecular dynamics simulations indicate …

Solvation thermodynamics from the perspective of endpoints DFT

RM Levy, N Matubayasi, BW Zhang - The Journal of Physical …, 2020 - ACS Publications
Solvation thermodynamics is concerned with the evaluation and physical interpretation of
solvation free energies. Endpoints DFT provides a framework for computing solvation free …