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[HTML][HTML] Single cell cancer epigenetics
M Casado-Pelaez, A Bueno-Costa, M Esteller - Trends in Cancer, 2022 - cell.com
Bulk sequencing methodologies have allowed us to make great progress in cancer
research. Unfortunately, these techniques lack the resolution to fully unravel the epigenetic …
research. Unfortunately, these techniques lack the resolution to fully unravel the epigenetic …
[HTML][HTML] Immune dysregulation
A Long, A Kleiner, RJ Looney - Journal of Allergy and Clinical Immunology, 2023 - Elsevier
The understanding of immune dysregulation in many different diseases continues to grow.
There is increasing evidence that altered microbiome and gut barrier dysfunction contribute …
There is increasing evidence that altered microbiome and gut barrier dysfunction contribute …
Epigenetic and transcriptomic reprogramming in monocytes of severe COVID-19 patients reflects alterations in myeloid differentiation and the influence of …
Background COVID-19 manifests with a wide spectrum of clinical phenotypes, ranging from
asymptomatic and mild to severe and critical. Severe and critical COVID-19 patients are …
asymptomatic and mild to severe and critical. Severe and critical COVID-19 patients are …
The Rapidly Expanding Genetic Spectrum of Common Variable Immunodeficiency–Like Disorders
The understanding of common variable immunodeficiency disorders (CVID) is in evolution.
CVID was previously a diagnosis of exclusion. New diagnostic criteria have allowed the …
CVID was previously a diagnosis of exclusion. New diagnostic criteria have allowed the …
Genetics and clinical phenotypes in common variable immunodeficiency
Common variable immunodeficiency (CVID) is one of the most common symptomatic groups
of inborn errors of immunity. In addition to infections resulting from insufficient levels of …
of inborn errors of immunity. In addition to infections resulting from insufficient levels of …
Interplay between epigenetic and genetic alterations in inborn errors of immunity
J Rodríguez-Ubreva, CL Calvillo, LRF Satter… - Trends in …, 2023 - cell.com
Inborn errors of immunity (IEIs) comprise a variety of immune conditions leading to
infections, autoimmunity, allergy, and cancer. Some IEIs have no identified mutation (s) …
infections, autoimmunity, allergy, and cancer. Some IEIs have no identified mutation (s) …
YAP/TAZ: Molecular pathway and disease therapy
Y Wei, VLZ Hui, Y Chen, R Han, X Han, Y Guo - MedComm, 2023 - Wiley Online Library
The Yes‐associated protein and its transcriptional coactivator with PDZ‐binding motif
(YAP/TAZ) are two homologous transcriptional coactivators that lie at the center of a key …
(YAP/TAZ) are two homologous transcriptional coactivators that lie at the center of a key …
Genomic crossroads between non-Hodgkin's lymphoma and common variable immunodeficiency
K Guevara-Hoyer, J Fuentes-Antrás… - Frontiers in …, 2022 - frontiersin.org
Common variable immunodeficiency (CVID) represents the largest group of primary
immunodeficiencies that may manifest with infections, inflammation, autoimmunity, and …
immunodeficiencies that may manifest with infections, inflammation, autoimmunity, and …
Common variable immunodeficiency, cross currents, and prevailing winds
Common variable immunodeficiency (CVID) is a heterogenous disease category created to
distinguish late‐onset antibody deficiencies from early‐onset diseases like …
distinguish late‐onset antibody deficiencies from early‐onset diseases like …
COVID-19 progression and convalescence in common variable immunodeficiency patients show dysregulated adaptive immune responses and persistent type I …
Common variable immunodeficiency (CVID) is the most prevalent primary
immunodeficiency, marked by hypogammaglobulinemia, poor antibody responses, and …
immunodeficiency, marked by hypogammaglobulinemia, poor antibody responses, and …