Atherosclerosis is the main risk factor for cardiovascular disease (CVD), which is the leading
cause of mortality worldwide. Atherosclerosis is initiated by endothelium activation and …

Atherosclerosis, formerly considered a bland lipid storage disease, actually involves an
ongoing inflammatory response. Recent advances in basic science have established a …

The recommendations listed in this CPG are, whenever possible, evidence based. An
extensive evidence review was conducted through October 2012, and other selected …

Alterations of endothelial cells and the vasculature play a central role in the pathogenesis of
a broad spectrum of the most dreadful of human diseases, as endothelial cells have the key …

Atherosclerosis is a chronic inflammatory disease; unstable atherosclerotic plaque rupture,
vascular stenosis, or occlusion caused by platelet aggregation and thrombosis lead to acute …

Over a hundred years ago, high doses of salicylates were shown to lower glucose levels in
diabetic patients. This should have been an important clue to link inflammation to the …

ContextComplications of atherosclerosis cause most morbidity and mortality in patients with
diabetes mellitus. Despite the frequency and severity of disease, proven medical therapy …

The recommendations listed in this CPG are, whenever possible, evidence based. An
extensive evidence review was conducted through October 2012, and other selected …

The ACC/AHA Task Force on Practice Guidelines was formed to make recommendations
regarding the diagnosis and treatment of patients with known or suspected cardiovascular …

Endothelial dysfunction is a systemic disorder and a key variable in the pathogenesis of
atherosclerosis and its complications. Current evidence suggests that endothelial status is …