The gut–liver axis and gut microbiota in health and liver disease

CL Hsu, B Schnabl - Nature Reviews Microbiology, 2023 - nature.com
The trillions of microorganisms in the human intestine are important regulators of health, and
disruptions in the gut microbial communities can cause disease. The gut, liver and immune …

Intestinal barrier in human health and disease

N Di Tommaso, A Gasbarrini, FR Ponziani - International journal of …, 2021 - mdpi.com
The intestinal mucosa provides a selective permeable barrier for nutrient absorption and
protection from external factors. It consists of epithelial cells, immune cells and their …

Nutritional components in Western diet versus Mediterranean diet at the gut microbiota–immune system interplay. Implications for health and disease

C García-Montero, O Fraile-Martínez… - Nutrients, 2021 - mdpi.com
The most prevalent diseases of our time, non-communicable diseases (NCDs)(including
obesity, type 2 diabetes, cardiovascular diseases and some types of cancer) are rising …

Gut–liver axis: barriers and functional circuits

O Pabst, MW Hornef, FG Schaap, V Cerovic… - Nature Reviews …, 2023 - nature.com
The gut and the liver are characterized by mutual interactions between both organs, the
microbiome, diet and other environmental factors. The sum of these interactions is …

Gut microbiome, liver immunology, and liver diseases

R Wang, R Tang, B Li, X Ma, B Schnabl… - Cellular & molecular …, 2021 - nature.com
The gut microbiota is a complex and plastic consortium of microorganisms that are intricately
connected with human physiology. The liver is a central immunological organ that is …

Alcohol-associated liver disease

B Mackowiak, Y Fu, L Maccioni… - The Journal of Clinical …, 2024 - Am Soc Clin Investig
Alcohol-associated liver disease (ALD) is a major cause of chronic liver disease worldwide,
and comprises a spectrum of several different disorders, including simple steatosis …

Multi-omics analyses of airway host–microbe interactions in chronic obstructive pulmonary disease identify potential therapeutic interventions

Z Yan, B Chen, Y Yang, X Yi, M Wei… - Nature …, 2022 - nature.com
The mechanistic role of the airway microbiome in chronic obstructive pulmonary disease
(COPD) remains largely unexplored. We present a landscape of airway microbe–host …

Contribution of the intestinal microbiome and gut barrier to hepatic disorders

DM Chopyk, A Grakoui - Gastroenterology, 2020 - Elsevier
Intestinal barrier dysfunction and dysbiosis contribute to development of diseases in liver
and other organs. Physical, immunologic, and microbiologic (bacterial, fungal, archaeal …

Gut microbiota as a trigger for metabolic inflammation in obesity and type 2 diabetes

TPM Scheithauer, E Rampanelli, M Nieuwdorp… - Frontiers in …, 2020 - frontiersin.org
The gut microbiota has been linked to the development of obesity and type 2 diabetes (T2D).
The underlying mechanisms as to how intestinal microbiota may contribute to T2D are only …

[HTML][HTML] The interaction among gut microbes, the intestinal barrier and short chain fatty acids

J Ma, X Piao, S Mahfuz, S Long, J Wang - Animal Nutrition, 2022 - Elsevier
The mammalian gut is inhabited by a massive and complicated microbial community, in
which the host achieves a stable symbiotic environment through the interdependence …