Cancer, metastasis, and the epigenome

S Kiri, T Ryba - Molecular Cancer, 2024 - Springer
Cancer is the second leading cause of death worldwide and disease burden is expected to
increase globally throughout the next several decades, with the majority of cancer-related …

[HTML][HTML] Epidemiology of spinal metastases, metastatic epidural spinal cord compression and pathologic vertebral compression fractures in patients with solid tumors …

R Van den Brande, EMJ Cornips, M Peeters… - Journal of bone …, 2022 - Elsevier
Introduction Spinal metastases (SM) are a frequent complication of cancer and may lead to
pathologic vertebral compression fractures (pVCF) and/or metastatic epidural spinal cord …

Genetically engineered myeloid cells rebalance the core immune suppression program in metastasis

S Kaczanowska, DW Beury, V Gopalan, AK Tycko… - Cell, 2021 - cell.com
Metastasis is the leading cause of cancer-related deaths, and greater knowledge of the
metastatic microenvironment is necessary to effectively target this process …

Siglec-15/sialic acid axis as a central glyco-immune checkpoint in breast cancer bone metastasis

Y Wang, Z Xu, KL Wu, L Yu, C Wang… - Proceedings of the …, 2024 - National Acad Sciences
Immunotherapy is a promising approach for treating metastatic breast cancer (MBC), offering
new possibilities for therapy. While checkpoint inhibitors have shown great progress in the …

Bone metastasis and skeletal-related events in patients with solid cancer: A Korean nationwide health insurance database study

S Hong, T Youk, SJ Lee, KM Kim, CM Vajdic - PLoS One, 2020 - journals.plos.org
Bone is one of the most common sites of metastasis from advanced solid tumors. Bone
metastasis is a leading cause of pain and increases the risk of skeletal-related events …

Polymers and inorganic nanoparticles: A winning combination towards assembled nanostructures for cancer imaging and therapy

K Yang, S Zhang, J He, Z Nie - Nano Today, 2021 - Elsevier
Inorganic nanoparticles show unique physical properties (eg, optical, electronic, magnetic
and catalytical properties), and highly tunable appearance characteristics (eg, size, shape …

[HTML][HTML] Management of bone health in solid tumours: From bisphosphonates to a monoclonal antibody

R von Moos, L Costa, E Gonzalez-Suarez… - Cancer treatment …, 2019 - Elsevier
Patients with solid tumours are at risk of impaired bone health from metastases and cancer
therapy-induced bone loss (CTIBL). We review medical management of bone health in …

Disrupting tumour vasculature and recruitment of aPDL1-loaded platelets control tumour metastasis

H Li, Z Wang, Z Chen, T Ci, G Chen, D Wen, R Li… - Nature …, 2021 - nature.com
Although therapies of cancer are advancing, it remains challenging for therapeutics to reach
the sites of metastasis, which accounts for majority of cancer associated death. In this study …

Radiomics for identification and prediction in metastatic prostate cancer: a review of studies

J Kendrick, R Francis, GM Hassan… - Frontiers in …, 2021 - frontiersin.org
Metastatic Prostate Cancer (mPCa) is associated with a poor patient prognosis. mPCa
spreads throughout the body, often to bones, with spatial and temporal variations that make …

Bisphosphonate-based conjugates and derivatives as potential therapeutic agents in osteoporosis, bone cancer and metastatic bone cancer

Z Mbese, BA Aderibigbe - International journal of molecular sciences, 2021 - mdpi.com
Metastatic bone cancer occurs in every type of cancer but is prevalent in lung, breast, and
prostate cancers. These metastases can cause extensive morbidity, including a range of …