Viruses are obligate intracellular parasites that depend on the host's protein synthesis
machinery for translating their mRNAs. The viral mRNA (vRNA) competes with the host …

Abstract Enterovirus 71 (EV71) poses serious threats to human health, particularly in
Southeast Asia, and no drugs or vaccines are available. Previous work identified the stem …

Hepatitis C virus is a single-stranded RNA based virus which can cause chronic HCV and
hepatocellular carcinoma. HCV genotype 3a has relatively higher rate of fibrosis …

Hepatitis C virus (HCV) subtypes are pre-requisite to predict endemicity, epidemiology,
clinical pathogenesis, diagnosis, and treatment of chronic hepatitis C infection. HCV …

Analytical ultracentrifugation (AUC) has emerged as a robust and reliable technique for
biomolecular characterization with extraordinary sensitivity. AUC is widely used to study …

Author Contribution FN performed the literature review and wrote the manuscript; STZ
coauthored, edited, and reviewed the manuscript. Abstract Treatment response in Hepatitis …

Being the most conserved region of all hepatitis C virus (HCV) genotypes and sub-
genotypes, the 5′ untranslated region (5′ UTR) of HCV genome signifies it's importance …

Abstract Enterovirus 71 (EV71), represents a persistent threat to global health and
economies, as outbreaks are reported in the United States and globally each year. Infections …

We herein report an RNA-targeting antiviral small molecule that reduces replication of the
human enterovirus 71 (EV71) via stabilization of an inhibitory small molecule-RNA-protein …

RNA viruses occupy a relevant position among the human pathogens, counting a
continuously increasing number of different species, which can cause more or less severe …