Hundreds of studies have found that weak magnetic fields can significantly influence various
biological systems. However, the underlying mechanisms behind these phenomena remain …

Glycogen synthase kinase-3 (GSK-3) is a widely expressed and highly conserved
serine/threonine protein kinase encoded in mammals by two genes that generate two …

The mammalian circadian system is a complex hierarchical temporal network which is
organized around an ensemble of uniquely coupled cells comprising the principal circadian …

Circadian rhythm disturbances are a common symptom among individuals with mood
disorders. The suprachiasmatic nucleus (SCN), in the ventral part of the anterior …

Despite advances in the treatment of bipolar disorder, a significant proportion of patients
experience disabling symptoms between episodes, and relapse rates are high. These …

In mammals, the circadian clocks network (central and peripheral oscillators) controls
circadian rhythms and orchestrates the expression of a range of downstream genes …

Circadian rhythms influence most of our life activities, notably getting up and going to sleep
every day. The new edition of this book delves into the mechanisms surrounding how these …

Lithium is commonly used to treat bipolar disorder, which is associated with altered
circadian rhythm. Lithium is a potent inhibitor of glycogen synthase kinase 3 (GSK3), which …

The suprachiasmatic nucleus (SCN) in the mammalian hypothalamus functions as an
endogenous pacemaker that generates and maintains circadian rhythms throughout the …

Posttranslational modifications play central roles in myriad biological pathways including
circadian regulation. We employed a circadian proteomic approach to demonstrate that …