Mucin type O‐glycosylation is one of the most diverse types of glycosylation, playing
essential roles in tissue development and homeostasis. In complex organisms, O‐GalNAc …

Mucin-type O-glycans are the primary constituents of mucins that are expressed on various
mucosal sites of the body, especially the bacteria-laden intestinal tract. Mucins are the main …

Genetically modified T cells expressing chimeric antigen receptors (CARs) demonstrate
robust responses against lineage restricted, non-essential targets in hematologic cancers …

Glycoproteins in animal cells contain a variety of glycan structures that are added co‐and/or
posttranslationally to proteins. Of over 20 different types of sugar–amino acid linkages …

Human core 1 β3-galactosyltransferase (C1β3Gal-T) generates the core 1 O-glycan Galβ1-
3GalNAcα1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in animal …

Mucin-type O-glycosylation is an evolutionarily conserved protein modification present on
membrane-bound and secreted proteins. Aberrations in O-glycosylation are responsible for …

Mucin-type O-linked oligosaccharides (O-glycans) are primary components of the intestinal
mucins that form the mucus gel layer overlying the gut epithelium. Impaired expression of …

We have explored the fundamental biological processes by which complex carbohydrates
expressed on cellular glycoproteins and glycolipids and in secretions of cells promote cell …

How peroxisomes are formed in eukaryotic cells is unknown but important for insight into a
variety of diseases. Both human and yeast cells lacking peroxisomes due to mutations in …

Dectin-1 is a C-type lectin-like receptor on leukocytes that mediates phagocytosis and
inflammatory mediator production in innate immunity to fungal pathogens. Dectin-1 lacks …