Precision public health in the era of genomics and big data

MC Roberts, KE Holt, G Del Fiol, AA Baccarelli… - Nature Medicine, 2024 - nature.com
Precision public health (PPH) considers the interplay between genetics, lifestyle and the
environment to improve disease prevention, diagnosis and treatment on a population level …

Genome-wide association testing beyond SNPs

L Harris, EM McDonagh, X Zhang, K Fawcett… - Nature Reviews …, 2024 - nature.com
Decades of genetic association testing in human cohorts have provided important insights
into the genetic architecture and biological underpinnings of complex traits and diseases …

Enhancing the Polygenic Score Catalog with tools for score calculation and ancestry normalization

SA Lambert, B Wingfield, JT Gibson, L Gil… - Nature Genetics, 2024 - nature.com
Polygenic scores (PGSs) have transformed human genetic research and have numerous
potential clinical applications. Here we present a series of recent enhancements to the PGS …

The NHGRI-EBI GWAS Catalog: standards for reusability, sustainability and diversity

M Cerezo, E Sollis, Y Ji, E Lewis, A Abid… - Nucleic Acids …, 2025 - academic.oup.com
Abstract The NHGRI-EBI GWAS Catalog serves as a vital resource for the genetic research
community, providing access to the most comprehensive database of human GWAS results …

Sexual trauma, Polygenic Scores, and Mental Health diagnoses and outcomes

AM Lake, Y Zhou, B Wang, VA Ky'Era, Y Zhang… - JAMA …, 2025 - jamanetwork.com
Importance Leveraging real-world clinical biobanks to investigate the associations between
genetic and environmental risk factors for mental illness may help direct clinical screening …

[HTML][HTML] Innovation in cancer pharmacotherapy through integrative consideration of germline and tumor genomes

R Tremmel, D Hübschmann, E Schaeffeler… - Pharmacological …, 2024 - Elsevier
Precision cancer medicine is widely established, and numerous molecularly targeted drugs
for various tumor entities are approved or in development. Personalized pharmacotherapy in …

[PDF][PDF] Integrating IoT in pediatric dental health: A data-driven approach to early prevention and education

EP Adeghe, CA Okolo, OT Ojeyinka - International Journal of …, 2024 - researchgate.net
This paper explores the integration of IoT devices, data analytics, and education techniques
to enhance pediatric dental health outcomes. By leveraging real-time data collection …

Advantages of using translation, paraphrasing, and podcasts to improve natural writing skills

E Suseno - IJIET (International Journal of Indonesian Education …, 2024 - e-journal.usd.ac.id
Most EFL students find it difficult to articulate themselves clearly in written assignments. To
overcome those flaws, twenty-five college students enrolled in the program. The WhatsApp …

The Polygenic Score Catalog: new functionality and tools to enable FAIR research

SA Lambert, B Wingfield, JT Gibson, L Gil… - medRxiv, 2024 - medrxiv.org
Polygenic scores (PGS) have transformed human genetic research and have multiple
potential clinical applications, including risk stratification for disease prevention and …

Methods for multiancestry genome‐wide association study meta‐analysis

CF Yap, AP Morris - Annals of Human Genetics, 2024 - Wiley Online Library
Genome‐wide association studies (GWAS) have significantly enhanced our understanding
of the genetic basis of complex diseases. Despite the technological advancements, gaps in …