Standardizing designed and emergent quantitative features in microphysiological systems
DM Nahon, R Moerkens, H Aydogmus… - Nature biomedical …, 2024 - nature.com
Microphysiological systems (MPSs) are cellular models that replicate aspects of organ and
tissue functions in vitro. In contrast with conventional cell cultures, MPSs often provide …
tissue functions in vitro. In contrast with conventional cell cultures, MPSs often provide …
Hippocampal subfield volumetry from structural isotropic 1 mm3 MRI scans: A note of caution
Spurred by availability of automatic segmentation software, in vivo MRI investigations of
human hippocampal subfield volumes have proliferated in the recent years. However, a …
human hippocampal subfield volumes have proliferated in the recent years. However, a …
A probabilistic atlas of the human thalamic nuclei combining ex vivo MRI and histology
The human thalamus is a brain structure that comprises numerous, highly specific nuclei.
Since these nuclei are known to have different functions and to be connected to different …
Since these nuclei are known to have different functions and to be connected to different …
Diagnosis of Alzheimer's disease using universum support vector machine based recursive feature elimination (USVM-RFE)
Alzheimer's disease is one of the most common causes of death in today's world. Magnetic
resonance imaging (MRI) provides an efficient and non-invasive approach for diagnosis of …
resonance imaging (MRI) provides an efficient and non-invasive approach for diagnosis of …
A deep learning model for early prediction of Alzheimer's disease dementia based on hippocampal magnetic resonance imaging data
Introduction It is challenging at baseline to predict when and which individuals who meet
criteria for mild cognitive impairment (MCI) will ultimately progress to Alzheimer's disease …
criteria for mild cognitive impairment (MCI) will ultimately progress to Alzheimer's disease …
Diffuse axonal injury has a characteristic multidimensional MRI signature in the human brain
Axonal injury is a major contributor to the clinical symptomatology in patients with traumatic
brain injury. Conventional neuroradiological tools, such as CT and MRI, are insensitive to …
brain injury. Conventional neuroradiological tools, such as CT and MRI, are insensitive to …
Independent and reproducible hippocampal radiomic biomarkers for multisite Alzheimer's disease: diagnosis, longitudinal progress and biological basis
Hippocampal morphological change is one of the main hallmarks of Alzheimer's disease
(AD). However, whether hippocampal radiomic features are robust as predictors of …
(AD). However, whether hippocampal radiomic features are robust as predictors of …
[HTML][HTML] Test-retest reliability of FreeSurfer automated hippocampal subfield segmentation within and across scanners
The human hippocampus is vulnerable to a range of degenerative conditions and as such,
accurate in vivo measurement of the hippocampus and hippocampal substructures via …
accurate in vivo measurement of the hippocampus and hippocampal substructures via …
Three-dimensional map** of neurofibrillary tangle burden in the human medial temporal lobe
PA Yushkevich, M Muñoz López… - Brain, 2021 - academic.oup.com
Tau protein neurofibrillary tangles are closely linked to neuronal/synaptic loss and cognitive
decline in Alzheimer's disease and related dementias. Our knowledge of the pattern of …
decline in Alzheimer's disease and related dementias. Our knowledge of the pattern of …
Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes
The hippocampus is a heterogeneous structure, comprising histologically distinguishable
subfields. These subfields are differentially involved in memory consolidation, spatial …
subfields. These subfields are differentially involved in memory consolidation, spatial …