Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions

MD Roberts, JJ McCarthy… - Physiological …, 2023‏ - journals.physiology.org
Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have
been extensively researched since the landmark report by Morpurgo (1897) of “work …

[HTML][HTML] The molecular athlete: exercise physiology from mechanisms to medals

R Furrer, JA Hawley, C Handschin - Physiological reviews, 2023‏ - journals.physiology.org
Human skeletal muscle demonstrates remarkable plasticity, adapting to numerous external
stimuli including the habitual level of contractile loading. Accordingly, muscle function and …

Resistance training recommendations to maximize muscle hypertrophy in an athletic population: Position stand of the IUSCA

B Schoenfeld, J Fisher, J Grgic, C Haun… - … Journal of Strength …, 2021‏ - journal.iusca.org
Hypertrophy can be operationally defined as an increase in the axial cross-sectional area of
a muscle fiber or whole muscle, and is due to increases in the size of pre-existing muscle …

Periodization and block periodization in sports: emphasis on strength-power training—a provocative and challenging narrative

MH Stone, WG Hornsby, GG Haff, AC Fry… - The Journal of …, 2021‏ - journals.lww.com
Abstract Stone, MH, Hornsby, WG, Haff, GG, Fry, AC, Suarez, DG, Liu, J, Gonzalez-Rave, JM,
and Pierce, KC. Periodization and block periodization in sports: emphasis on strength-power …

Muscle hypertrophy and muscle strength: dependent or independent variables? A provocative review

C Reggiani, S Schiaffino - European journal of translational …, 2020‏ - pmc.ncbi.nlm.nih.gov
The question whether the muscle hypertrophy induced by resistance training, hormone
administration or genetic manipulation is accompanied by a proportional increase in muscle …

[HTML][HTML] Making sense of muscle protein synthesis: a focus on muscle growth during resistance training

OC Witard, L Bannock… - … journal of sport …, 2021‏ - journals.humankinetics.com
The acute response of muscle protein synthesis (MPS) to resistance exercise and nutrition is
often used to inform recommendations for exercise programming and dietary interventions …

Skeletal muscle DNA methylation and mRNA responses to a bout of higher versus lower load resistance exercise in previously trained men

CL Sexton, JS Godwin, MC McIntosh, BA Ruple… - Cells, 2023‏ - mdpi.com
We sought to determine the skeletal muscle genome-wide DNA methylation and mRNA
responses to one bout of lower load (LL) versus higher load (HL) resistance exercise …

Impact of physical activity and exercise on the epigenome in skeletal muscle and effects on systemic metabolism

J Plaza-Diaz, D Izquierdo, Á Torres-Martos, AT Baig… - Biomedicines, 2022‏ - mdpi.com
Exercise and physical activity induces physiological responses in organisms, and
adaptations in skeletal muscle, which is beneficial for maintaining health and preventing …

Metabolic reprogramming underlies cavefish muscular endurance despite loss of muscle mass and contractility

L Olsen, M Levy, JK Medley, H Hassan, B Miller… - Proceedings of the …, 2023‏ - pnas.org
Physical inactivity is a scourge to human health, promoting metabolic disease and muscle
wasting. Interestingly, multiple ecological niches have relaxed investment into physical …

Optimizing Resistance Training for Sprint and Endurance Athletes: Balancing Positive and Negative Adaptations

B Van Hooren, P Aagaard, AJ Blazevich - Sports Medicine, 2024‏ - Springer
Resistance training (RT) triggers diverse morphological and physiological adaptations that
are broadly considered beneficial for performance enhancement as well as injury risk …