The high-throughput-next generation sequencing (HT-NGS) technologies are currently the
hottest topic in the field of human and animals genomics researches, which can produce …

Animal models of human diseases play a critical role in medical research. Pigs are
anatomically and physiologically more like humans than are small rodents such as mice …

Traditionally, one giraffe species and up to eleven subspecies have been recognized [1];
however, nine subspecies are commonly accepted [2]. Even after a century of research, the …

Comparative medicine is founded on the concept that other animal species share
physiological, behavioral, or other characteristics with humans. Over 2,400 years ago it was …

Traditional biomedical models are easy to manage in experimental facilities and allow fast
and affordable basic genetic studies related to human disorders, but in some cases they do …

Inbreeding has long been recognized as a primary cause of fitness reduction in both wild
and domesticated populations. Consanguineous matings cause inheritance of haplotypes …

The use of pigs in neuroscience research has increased in the past decade, which has seen
broader recognition of the potential of pigs as an animal for experimental modeling of …

The translation of novel discoveries from basic research to clinical application is a long,
often inefficient, and thus costly process. Accordingly, the process of drug development …

The established causal genes in Alzheimer's disease (AD), APP, PSEN1, and PSEN2, are
functionally characterized using biomarkers, capturing an in vivo profile reflecting the …

The spatio-temporal expression patterns of Circular RNA (circRNA) across organs and
developmental stages are critical for its function and evolution analysis. However, they …