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Genetics, epigenetics, cellular immunology, and gut microbiota: emerging links with Graves' disease
F Zhou, X Wang, L Wang, X Sun, G Tan… - Frontiers in Cell and …, 2022 - frontiersin.org
Graves' disease (GD) is a well-known organ-specific autoimmune disease characterized by
hyperthyroidism, goiter, and exophthalmos. The incidence of GD is approximately 2.0–3.0 …
hyperthyroidism, goiter, and exophthalmos. The incidence of GD is approximately 2.0–3.0 …
Precision cardio-oncology: a systems-based perspective on cardiotoxicity of tyrosine kinase inhibitors and immune checkpoint inhibitors
Cancer therapies have been evolving from conventional chemotherapeutics to targeted
agents. This has fulfilled the hope of greater efficacy but unfortunately not of greater safety …
agents. This has fulfilled the hope of greater efficacy but unfortunately not of greater safety …
Genetic association study of IL2RA, IFIH1, and CTLA-4 polymorphisms with autoimmune thyroid diseases and type 1 diabetes
H Borysewicz-Sańczyk, B Sawicka… - Frontiers in …, 2020 - frontiersin.org
Autoimmune thyroid diseases (AITDs) which include Graves' disease (GD) and Hashimoto's
thyroiditis (HT) as well as type 1 diabetes (T1D) are common autoimmune disorders in …
thyroiditis (HT) as well as type 1 diabetes (T1D) are common autoimmune disorders in …
Association and gene–gene interaction analyses for polymorphic variants in CTLA-4 and FOXP3 genes: role in susceptibility to autoimmune thyroid disease
N Fathima, P Narne, M Ishaq - Endocrine, 2019 - Springer
Purpose Polymorphic variants of cytotoxic T-lymphocyte antigen-4 (CTLA-4) and forkhead
box protein P3 (FOXP3) genes are implicated in dysregulated immune homeostasis and …
box protein P3 (FOXP3) genes are implicated in dysregulated immune homeostasis and …
Inborn errors of immunity and their phenocopies: CTLA4 and PD-1
Y Hao, MC Cook - Frontiers in immunology, 2022 - frontiersin.org
Elucidating links between genotype and phenotype in patients with rare inborn errors of
immunity (IEIs) provides insights into mechanisms of immune regulation. In many autosomal …
immunity (IEIs) provides insights into mechanisms of immune regulation. In many autosomal …
Genetic variant association of PTPN22, CTLA4, IL2RA, as well as HLA frequencies in susceptibility to alopecia areata
Alopecia areata (AA) is characterized by a genetically complex inheritance. HLA
frequencies, as well as the single nucleotide polymorphism (SNP) in PTPN22, CTLA4, and …
frequencies, as well as the single nucleotide polymorphism (SNP) in PTPN22, CTLA4, and …
An animal model of abacavir-induced HLA-mediated liver injury
Genome-wide association studies indicate that several idiosyncratic adverse drug reactions
are highly associated with specific human leukocyte antigen (HLA) alleles. For instance …
are highly associated with specific human leukocyte antigen (HLA) alleles. For instance …
Is There a Link between Thyroid Peroxidase Gene Promoter Polymorphisms and Autoimmune Thyroiditis in the Polish Population?
K Lacka, A Maciejewski, P Jarecki, W Herman… - International Journal of …, 2024 - mdpi.com
(1) Autoimmune thyroiditis (AIT) is the most common cause of primary hypothyroidism and
one of the most frequent organ-specific autoimmune diseases. Its pathogenesis is polygenic …
one of the most frequent organ-specific autoimmune diseases. Its pathogenesis is polygenic …
Association between polymorphisms of IL-23/IL-17 pathway and clinical phenotypes of autoimmune thyroid diseases
T Cai, G Wang, Y Yang, K Mu, J Zhang… - Iranian journal of …, 2022 - iji.sums.ac.ir
Background: Several autoimmune and inflammatory disorders, including autoimmune
thyroid diseases (AITD), have been linked to Th17 cells and the IL-23/IL-17 axis. Current …
thyroid diseases (AITD), have been linked to Th17 cells and the IL-23/IL-17 axis. Current …
[PDF][PDF] HashimotoTs Thyroiditis 7
WM Wiersinga - Thyroid Diseases, 2018 - ndl.ethernet.edu.et
Hashimoto's thyroiditis is best defined as an organ-specific autoimmune disease,
characterized by autoimmune-mediated destruction of the thyroid gland. Diagnostic criteria …
characterized by autoimmune-mediated destruction of the thyroid gland. Diagnostic criteria …