Activation of PI3K (phosphoinositide 3-kinase) is a shared response to engagement of
diverse types of transmembrane receptors. Depending on the cell type and stimulus, PI3K …

The ubiquitously expressed phosphoinositide 3-kinase (PI3K) family of lipid kinases control
diverse cellular functions including cell survival, proliferation, metabolism and migration …

Glucocorticoids have been used for decades to treat lymphomas without an established
mechanism of action. Using functional genomic, proteomic, and chemical screens, we …

Parasites, including African trypanosomes, utilize several immune evasion strategies to
ensure their survival and completion of their life cycles within their hosts. The defense factors …

Germinal centers (GCs) are sites of rapid B‐cell proliferation and somatic mutation. These
ovoid structures develop within the center of follicles and grow to a stereotypic size. The cell …

Sarcoidosis and tuberculosis (TB) are two granulomatous diseases that often share
overlap** clinical features, including uveitis. We measured 368 inflammation-related …

Breast cancer remains the second cause of tumor‐related mortality in women worldwide
mainly due to chemoresistance and metastasis. The chemoresistance and metastasis are …

The phosphoinositide 3-kinase (PI3K) pathway is a central signal transduction axis
controlling normal B cell homeostasis and activation in humoral immunity. The p110δ PI3K …

Multiple Myeloma (MM) is an incurable plasma cell malignancy primarily localized within the
bone marrow (BM). It develops from a premalignant stage, monoclonal gammopathy of …

This preliminary study aimed to screen non-coding RNAs (ncRNAs) from plasma exosomes
as a new method for cervical cancer diagnosis. Differentially expressed RNAs were initially …