Metastasis involves the spread of cancer cells from the primary tumor to surrounding tissues
and to distant organs and is the primary cause of cancer morbidity and mortality. In order to …

Glioblastoma (GBM) is an incurable brain tumor with a median survival of approximately 15
months despite an aggressive standard of care that includes surgery, chemotherapy, and …

Glioblastoma is an immunosuppressive, fatal brain cancer that contains glioblastoma stem-
like cells (GSCs). Oncolytic herpes simplex virus (oHSV) selectively replicates in cancer …

Glioblastoma (GBM) is the most lethal primary adult brain tumor and its pathology is
hallmarked by distorted neovascularization, diffuse tumor-associated macrophage …

Immunotherapy has emerged as a promising approach to treat cancer, however, its efficacy
in highly malignant brain-tumors, glioblastomas (GBM), is limited. Here, we generate distinct …

Glioblastoma is the most common malignant primary central nervous system tumor and one
of the most debilitating cancers. The prognosis of patients with glioblastoma remains poor …

Glioblastoma remains a lethal diagnosis with a 5-year survival rate of less than 10%.(NEJM
352: 987-96, 2005) Although immunotherapy-based approaches are capable of inducing …

Glioblastoma (GBM) is an aggressive primary human brain tumour that has resisted effective
therapy for decades. Although glucose and glutamine are the major fuels that drive GBM …

Glioblastoma (GBM) is resistant to immune checkpoint inhibition due to its low mutation rate,
phosphatase and tensin homologue (PTEN)-deficient immunosuppressive …

Background Glioblastoma (GBM) is the most common malignant tumour of the central
nervous system. Despite recent advances in multimodal GBM therapy incorporating surgery …