The potential of endurance exercise-derived exosomes to treat metabolic diseases

A Safdar, A Saleem, MA Tarnopolsky - Nature Reviews Endocrinology, 2016 - nature.com
Endurance exercise-mediated multisystemic adaptations are known to mitigate metabolism-
related disorders such as obesity and type 2 diabetes mellitus (T2DM). However, the …

The pandemic of physical inactivity: global action for public health

HW Kohl, CL Craig, EV Lambert, S Inoue, JR Alkandari… - The lancet, 2012 - thelancet.com
Physical inactivity is the fourth leading cause of death worldwide. We summarise present
global efforts to counteract this problem and point the way forward to address the pandemic …

Productivity loss due to overweight and obesity: a systematic review of indirect costs

A Goettler, A Grosse, D Sonntag - BMJ open, 2017 - bmjopen.bmj.com
Objective The increasingly high levels of overweight and obesity among the workforce are
accompanied by a hidden cost burden due to losses in productivity. This study reviews the …

Physical inactivity: a risk factor and target for intervention in renal care

DM Zelle, G Klaassen, E Van Adrichem… - Nature Reviews …, 2017 - nature.com
Regular physical activity is associated with an increased quality of life and reduced
morbidity and mortality in the general population and in patients with chronic kidney disease …

Inadequate physical activity and health care expenditures in the United States

SA Carlson, JE Fulton, M Pratt, Z Yang… - Progress in cardiovascular …, 2015 - Elsevier
This study estimates the percentage of health care expenditures in the non-institutionalized
United States (US) adult population associated with levels of physical activity inadequate to …

The epidemiology of obesity in reproduction

B Ahmed, JC Konje - Best Practice & Research Clinical Obstetrics & …, 2023 - Elsevier
Over the last decades, overweight and obesity rates have been rising exponentially and
have now reached epidemic proportions. These are significantly higher in women than men …

School‐based physical activity programs for promoting physical activity and fitness in children and adolescents aged 6 to 18

SE Neil-Sztramko, H Caldwell… - Cochrane database of …, 2021 - cochranelibrary.com
Background Physical activity among children and adolescents is associated with lower
adiposity, improved cardio‐metabolic health, and improved fitness. Worldwide, fewer than …

Exercise modulates oxidative stress and inflammation in aging and cardiovascular diseases

N Sallam, I Laher - Oxidative medicine and cellular longevity, 2016 - Wiley Online Library
Despite the wealth of epidemiological and experimental studies indicating the protective role
of regular physical activity/exercise training against the sequels of aging and cardiovascular …

Oxygen consumption and usage during physical exercise: the balance between oxidative stress and ROS-dependent adaptive signaling

Z Radak, Z Zhao, E Koltai, H Ohno… - Antioxidants & redox …, 2013 - liebertpub.com
The complexity of human DNA has been affected by aerobic metabolism, including
endurance exercise and oxygen toxicity. Aerobic endurance exercise could play an …

[HTML][HTML] Chronic disease and the link to physical activity

JL Durstine, B Gordon, Z Wang, X Luo - Journal of sport and health science, 2013 - Elsevier
Chronic diseases have become a focal point of public health worldwide with estimates of
trillions of dollars in annual health care cost and causing more than 36 million deaths a year …