The role of matrix metalloproteinases (MMP-8, MMP-9, MMP-13) in periodontal and peri-implant pathological processes

I Luchian, A Goriuc, D Sandu, M Covasa - International Journal of …, 2022 - mdpi.com
Severe periodontitis, a destructive inflammatory disease of the supporting tissues of the
teeth, ranks sixth in terms of global spread, affecting about 11% of the population …

Matrix metalloproteinases as regulators of periodontal inflammation

C Franco, HR Patricia, S Timo, B Claudia… - International journal of …, 2017 - mdpi.com
Periodontitis are infectious diseases characterized by immune-mediated destruction of
periodontal supporting tissues and tooth loss. Matrix metalloproteinases (MMPs) are key …

Periodontal health and disease: The contribution of genetics

LM Shaddox, LA Morford, L Nibali - Periodontology 2000, 2021 - Wiley Online Library
Periodontitis is an infectious, inflammatory disease that is associated with a complex
interplay between specific bacteria, host response, and environmental factors. Because of its …

Genetic factors and the risk of periodontitis development: Findings from a systematic review composed of 13 studies of meta‐analysis with 71,531 participants

MK da Silva, ACG de Carvalho… - … journal of dentistry, 2017 - Wiley Online Library
Purpose. This work aimed to synthesize the results of recent meta‐analysis focusing on
polymorphism in inflammatory mediators and its relation with the risk of periodontitis …

Matrix Metalloproteinases in Oral Health—Special Attention on MMP-8

T Atanasova, T Stankova, A Bivolarska, T Vlaykova - Biomedicines, 2023 - mdpi.com
Matrix metalloproteinases (MMPs) are a large family of Ca2+ and Zn2+ dependent
proteolytic enzymes, able to cleave the various components of the extracellular matrix …

Saliva and serum biomarkers in periodontitis and coronary artery disease

LSJ Lahdentausta, S Paju, P Mäntylä… - Journal of clinical …, 2018 - Wiley Online Library
Abstract Aim Matrix metalloproteinase (MMP)‐8, MMP‐9, tissue inhibitor of matrix
metalloproteinase (TIMP)‐1 and myeloperoxidase (MPO) participate in extracellular matrix …

Effect of aging on homeostasis in the soft tissue of the periodontium: A narrative review

YG Kim, SM Lee, S Bae, T Park, H Kim, Y Jang… - Journal of personalized …, 2021 - mdpi.com
Aging is characterized by a progressive decline or loss of physiological functions, leading to
increased susceptibility to disease or death. Several aging hallmarks, including genomic …

The genetic aspects of periodontitis pathogenesis and the regenerative properties of stem cells

K Ustianowska, Ł Ustianowski, E Bakinowska… - Cells, 2024 - mdpi.com
Periodontitis (PD) is a prevalent and chronic inflammatory disease with a complex
pathogenesis, and it is associated with the presence of specific pathogens, such as …

Periodontal disease pathogens, pathogenesis, and therapeutics: the CRISPR-Cas effect

MN Kedlaya, L Puzhankara, R Prasad, A Raj - The CRISPR Journal, 2023 - liebertpub.com
Periodontal disease (PD) is an immune-inflammatory disease affecting the supporting
structures of the teeth, which results in progressive destruction of the hard and soft tissues …

The Association of Matrix Metalloproteinase‐1,‐2,‐3,‐7, and‐13 Gene Polymorphisms With Peri‐Implantitis in an Iranian Population: A Case–Control Study

L Saremi, S Shahbazi, ME Ghaffari… - Clinical and …, 2024 - Wiley Online Library
Objectives Peri‐implantitis (PI) is the most common biological issue surrounding dental
implants. According to current knowledge, the aforementioned complication is not equally …