Sexual development in Plasmodium parasites: knowing when it's time to commit

GA Josling, M Llinás - Nature Reviews Microbiology, 2015 - nature.com
Malaria is a devastating infectious disease that is caused by blood-borne apicomplexan
parasites of the genus Plasmodium. These pathogens have a complex lifecycle, which …

A latent ability to persist: differentiation in Toxoplasma gondii

V Jeffers, Z Tampaki, K Kim, WJ Sullivan - Cellular and Molecular Life …, 2018 - Springer
A critical factor in the transmission and pathogenesis of Toxoplasma gondii is the ability to
convert from an acute disease-causing, proliferative stage (tachyzoite), to a chronic, dormant …

ApiAP2 transcription factors in apicomplexan parasites

MD Jeninga, JE Quinn, M Petter - Pathogens, 2019 - mdpi.com
Apicomplexan parasites are protozoan organisms that are characterised by complex life
cycles and they include medically important species, such as the malaria parasite …

Opposing Transcriptional Mechanisms Regulate Toxoplasma Development

DP Hong, JB Radke, MW White - Msphere, 2017 - Am Soc Microbiol
The Toxoplasma biology that underlies human chronic infection is developmental
conversion of the acute tachyzoite stage into the latent bradyzoite stage. We investigated the …

[HTML][HTML] Advances towards the complete in vitro life cycle of Toxoplasma gondii

D Warschkau, F Seeber - Faculty Reviews, 2023 - ncbi.nlm.nih.gov
The full life cycle of Toxoplasma gondii cannot be recapitulated in vitro, and access to
certain stages, such as mature tissue cysts (bradyzoites) and oocysts (sporozoites) …

Genome-wide localization of histone variants in Toxoplasma gondii implicates variant exchange in stage-specific gene expression

SC Nardelli, NC Silmon de Monerri, L Vanagas… - BMC genomics, 2022 - Springer
Background Toxoplasma gondii is a protozoan parasite that differentiates from acute
tachyzoite stages to latent bradyzoite forms in response to environmental cues that modify …

Transcriptome modulation of bovine trophoblast cells in vitro by Neospora caninum

P Horcajo, L Jiménez-Pelayo… - International journal for …, 2017 - Elsevier
Neospora caninum is one of the most efficient transplacentally transmitted pathogens in
cattle and is a cause of abortion in this domestic species. The invasion and proliferation of …

[HTML][HTML] Comparative tachyzoite proteome analyses among six Neospora caninum isolates with different virulence

L Rico-San Román, P Horcajo… - International journal for …, 2020 - Elsevier
The biological variability among Neospora caninum isolates has been widely shown,
however, the molecular basis that determines this diversity has not been thoroughly …

Dissection of the in vitro developmental program of Hammondia hammondi reveals a link between stress sensitivity and life cycle flexibility in Toxoplasma gondii

SL Sokol, AS Primack, SC Nair, ZS Wong, M Tembo… - Elife, 2018 - elifesciences.org
Most eukaryotic parasites are obligately heteroxenous, requiring sequential infection of
different host species in order to survive. Toxoplasma gondii is a rare exception to this rule …

Toxoplasma gondii Me49 and NED strains arrest host cell cycle progression and alter chromosome segregation in a strain-independent manner

L Rojas-Barón, C Hermosilla, A Taubert… - Frontiers in …, 2024 - frontiersin.org
Toxoplasma gondii is an obligate intracellular parasite that modulates a broad range of host
cell functions to guarantee its intracellular development and replication. T. gondii includes …