Most of the genome is transcribed into RNA but only 2% of the sequence codes for proteins.
Non-coding RNA transcripts include a very large number of long noncoding RNAs …

Long non-coding RNAs (lncRNAs) have been identified as master gene regulators through
various mechanisms such as transcription, translation, protein modification and RNA-protein …

Gastric cancer (GC) is one of the most leading cause of malignancies. However, the
molecular mechanisms underlying stomach carcinogenesis remain incompletely …

Neuroblastoma (NB) is a challenging pediatric extracranial solid tumor characterized by a
poor prognosis and resistance to chemotherapy. Identifying targets to enhance …

Simple Summary Long non-coding RNA (lncRNA) is a type of RNA molecule that show
striking resemblance to mRNA in terms of synthesis and structure but lacks protein coding …

Neuroblastoma is the most common malignant extracranial solid tumor of childhood. Recent
studies involving the application of advanced high-throughput “omics” techniques have …

The role of long non‐coding RNAs (lncRNAs) in p53‐mediated tumor suppression has
become increasingly appreciated in the past decade. Thus, the identification of p53 …

Ursolic acid (UA) is an accessible triterpenoid, widely applied in the design and synthesis of
antitumor compounds. However, the mechanism of its anti-tumor effect is still unclear. To …

The p53 tumor suppressor protein, a sequence-specific DNA binding transcription factor,
regulates the expression of a large number of genes, in response to various forms of cellular …

Neuroblastoma accounts for 15% of cancer-related deaths in children, highlighting an unmet
need for novel therapies. Selinexor is a small molecule inhibitor of XPO1. XPO1 shuffles …