Protective effects of curcumin against doxorubicin-induced toxicity and resistance: A review

M Mohajeri, A Sahebkar - Critical reviews in oncology/hematology, 2018‏ - Elsevier
Doxorubicin (DOX)-induced toxicity and resistance are major obstacles in chemotherapeutic
approaches. Despite effective in the treatment of numerous malignancies, some clinicians …

Protective effect of kaempferol and its nanoparticles on 5‐fluorouracil‐induced cardiotoxicity in rats

S Safarpour, M Pirzadeh, A Ebrahimpour… - BioMed Research …, 2022‏ - Wiley Online Library
Background. Fluorouracil (5‐FU) is the third most common chemotherapeutic agent used in
the treatment of solid tumors. 5‐FU‐associated cardiotoxicity ranks the second causes of …

Colchicine ameliorates 5‐Fluorouracil‐Induced cardiotoxicity in rats

S Safarpour, S Safarpour, M Pirzadeh… - Oxidative Medicine …, 2022‏ - Wiley Online Library
Background and Objective. 5‐Fluorouracil is one of the most common chemotherapeutic
agents used in the treatment of solid tumors. 5‐Fluorouracil‐associated cardiotoxicity is the …

Fisetin, a plant flavonoid ameliorates doxorubicin-induced cardiotoxicity in experimental rats: the decisive role of caspase-3, COX-II, cTn-I, iNOs and TNF-α

T Ma, AD Kandhare, AA Mukherjee-Kandhare… - Molecular biology …, 2019‏ - Springer
Doxorubicin (DOX) is a widely used anthracycline antibiotic for the management of
carcinoma. However, it is associated with cardiotoxicity. Fisetin is a plant flavonoid reported …

Ferroptosis as a molecular target of epigallocatechin gallate in diseases

L Wang, C Tang, Q Zhang, Q Pan - Archives of Physiology and …, 2024‏ - Taylor & Francis
Context Ferroptosis is a novel form of cell death characterised by iron overload and lipid
peroxidation. It is closely associated with many diseases, including cardiovascular diseases …

[HTML][HTML] Exploring the mechanism of curcumin in the treatment of doxorubicin-induced cardiotoxicity based on network pharmacology and molecular docking …

Z Hu - Medicine, 2024‏ - journals.lww.com
Doxorubicin (DOX) is one of the most effective chemotherapeutic agents. However, the
nonselective effect leads to serious cardiotoxicity risk in clinical use. Curcumin is a well …

Protective mechanisms of coenzyme-Q10 may involve up-regulation of testicular P-glycoprotein in doxorubicin-induced toxicity

AAK El-Sheikh, MA Morsy, MM Mahmoud… - Environmental …, 2014‏ - Elsevier
The anticancer drug; doxorubicin (DOX), causes testicular toxicity as an adverse effect. P-
glycoprotein (P-gp) is a multidrug resistance efflux transporter expressed in blood-testis …

Phoenix dactylifera Protects against Doxorubicin‐Induced Cardiotoxicity and Nephrotoxicity

Y Wang, X Chao, FD Ahmad, H Shi… - Cardiology …, 2019‏ - Wiley Online Library
Doxorubicin (DOX) is an important anticancer drug used widely in the treatment of leukemia
and lymphoma. The suitability of DOX is enhanced by its high therapeutic index, but its …

Cardioprotective effect of allyl isothiocyanate in a rat model of doxorubicin acute toxicity

S Waz, AI Matouk - Toxicology Mechanisms and Methods, 2022‏ - Taylor & Francis
Doxorubicin (DOX) is an effective anthracycline chemotherapeutic drug. Nevertheless, the
cardiotoxicity adverse effect restricts its clinical benefit. Allyl isothiocyanate (AITC) is a …

Effect of infliximab, a tumor necrosis factor-alpha inhibitor, on doxorubicin-induced nephrotoxicity in rats

AM Abdelrahman, YM Al Suleimani, P Manoj… - Naunyn-Schmiedeberg's …, 2020‏ - Springer
Abstract Treatment with the chemotherapeutic agent, doxorubicin (DOX), is limited by
nephrotoxicity. We investigated the possible protective effect of infliximab, a tumor necrosis …