Prospective birth cohort studies tracking asthma initiation and consolidation in community
cohorts have identified viral infections occurring against a background of allergic …

Because of its essential role in gas exchange and oxygen delivery, the lung has evolved a
variety of strategies to control inflammation and maintain homeostasis. Invasion of the lung …

Research on the pathogenesis of asthma has traditionally concentrated on environmental
stimuli, genetic susceptibilities, adaptive immune responses, and end-organ alterations …

Rationale: The extent to which maternal smoking in pregnancy (MSP) has persisting effects
on respiratory health remains uncertain and the mechanisms involved are not fully …

Pollen proteins can act as antigens for the human immune system and are capable of
exacerbating allergic rhinoconjunctivitis (pollinosis) and allergic asthma. Allergic reactions …

Toll-like receptors (TLR) belong to a large family of pattern recognition receptors known as
the ancient 'gatekeepers' of the immune system. TLRs are located at the first line of defense …

Virus infection and allergy in the development of asthma: wh... : Current Opinion in Allergy and
Clinical Immunology Virus infection and allergy in the development of asthma: what is the …

Asthma is a complex multigenic disease. The most frequently encountered form is atopic
asthma, which is at its highest prevalence during childhood/young adulthood, and this …

The immune response plays an important role in the pathophysiology of numerous diseases
including asthma, autoimmunity and cancer. Application of biomarkers of immunotoxicity in …

Background Although most children with asthma and rhinitis are sensitized to aeroallergens,
only a minority of sensitized children are symptomatic, implying the underlying operation of …