Systematic bone loss is commonly complicated with inflammatory bowel diseases (IBDs)
with unclear pathogenesis and uncertain treatment. In experimental colitis mouse models …

Clinical studies revealed a relationship between osteoporosis and sarcopenia. Based on
this background, crosstalk between muscle and bone has emerged as a novel research field …

It is important to prevent not only diabetic complications but also diabetic comorbidities in
diabetes care. We have elucidated multifaceted insulin action in various tissues mainly by …

Whole body vibration (WBV) is a form of passive exercise by the stimulation of mechanical
vibration platform. WBV has been extensively investigated through clinical studies with main …

Sarcopenia, a condition characterized by gradual loss of skeletal muscle mass and function,
is a complex diagnosis; the decisive criterion in this diagnosis is the measurement of …

This study examines the interplay between ambient temperature, brown adipose tissue
(BAT) function, and bone metabolism, emphasizing the effects of cold exposure and BAT …

Background Aging leads to sarcopenia, which is characterized by reduced muscle mass and
strength. Many factors, including altered muscle protein turnover, diminished neuromuscular …

Introduction Apolipoprotein E4 (APOE4) is the strongest genetic risk factor for Alzheimer's
disease (AD), yet it's unclear how this allele mediates risk. APOE4 carriers experience …

Background: The association between pretreatment skeletal muscle index (SMI) and long-
term survival of pancreatic carcinoma patients remains unclear up to now. Methods: The …

Insulin is a hormone that positively regulates anabolism and cell growth, whereas diabetes
mellitus is a disease characterized by hyperglycemia associated with impaired insulin …