[HTML][HTML] Codon-based indices for modeling gene expression and transcript evolution
S Bahiri-Elitzur, T Tuller - Computational and Structural Biotechnology …, 2021 - Elsevier
Codon usage bias (CUB) refers to the phenomena that synonymous codons are used in
different frequencies in most genes and organisms. The general assumption is that codon …
different frequencies in most genes and organisms. The general assumption is that codon …
Mechanisms and Delivery of tRNA Therapeutics
C Ward, A Beharry, R Tennakoon, P Rozik… - Chemical …, 2024 - ACS Publications
Transfer ribonucleic acid (tRNA) therapeutics will provide personalized and mutation
specific medicines to treat human genetic diseases for which no cures currently exist. The …
specific medicines to treat human genetic diseases for which no cures currently exist. The …
Codon and codon-pair usage tables (CoCoPUTs): facilitating genetic variation analyses and recombinant gene design
Usage of sequential codon-pairs is non-random and unique to each species. Codon-pair
bias is related to but clearly distinct from individual codon usage bias. Codon-pair bias is …
bias is related to but clearly distinct from individual codon usage bias. Codon-pair bias is …
Towards controlled terminology for reporting germline cancer susceptibility variants: an ENIGMA report
The vocabulary currently used to describe genetic variants and their consequences reflects
many years of studying and discovering monogenic disease with high penetrance. With the …
many years of studying and discovering monogenic disease with high penetrance. With the …
LncRNA FLG-AS1 mitigates diabetic retinopathy by regulating retinal epithelial cell inflammation, oxidative stress, and apoptosis via miR-380-3p/SOCS6 axis
R Luo, L Li, F **ao, J Fu - Inflammation, 2022 - Springer
The objective of this study is to investigate lncRNA FLG-AS1-mediated miR-380-3p/SOCS6
axis in inflammation, oxidative stress, and apoptosis of retinal epithelial cells in diabetic …
axis in inflammation, oxidative stress, and apoptosis of retinal epithelial cells in diabetic …
[HTML][HTML] Does proteostasis get lost in translation? Implications for protein aggregation across the lifespan
Protein aggregation is a phenomenon of major relevance in neurodegenerative and
neuromuscular disorders, cataracts, diabetes and many other diseases. Research has …
neuromuscular disorders, cataracts, diabetes and many other diseases. Research has …
Codon usage is influenced by compositional constraints in genes associated with dementia
Dementia is a clinical syndrome characterized by progressive cognitive decline, and the
symptoms could be gradual, persistent, and progressive. In the present study, we …
symptoms could be gradual, persistent, and progressive. In the present study, we …
Effects of rrm1 on NNV Resistance Revealed by RNA-seq and Gene Editing
Viral nervous necrosis (VNN) disease caused by the nervous necrosis virus (NNV) is a
major disease, leading to a huge economic loss in aquaculture. Previous GWAS and QTL …
major disease, leading to a huge economic loss in aquaculture. Previous GWAS and QTL …
[HTML][HTML] Analysis of synonymous codon usage patterns of HPRT1 gene across twelve mammalian species
Genetic changes in Hypoxanthine guanine phosphoribosyltransferace (HPRT1) gene can
alter the expression of the dopamine neurotransmitter leads to abnormal neuron function, a …
alter the expression of the dopamine neurotransmitter leads to abnormal neuron function, a …
CUBAP: an interactive web portal for analyzing codon usage biases across populations
Synonymous codon usage significantly impacts translational and transcriptional efficiency,
gene expression, the secondary structure of both mRNA and proteins, and has been …
gene expression, the secondary structure of both mRNA and proteins, and has been …