Nonalcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease.
NAFLD often occurs associated with endocrinopathies. Evidence suggests that endocrine …

Glucocorticoids (GCs) are hormones that aid the body under stress by regulating glucose
and free fatty acids. GCs maintain energy homeostasis in multiple tissues, including those in …

Adiposity varies among individuals with the influence of diverse physiological, pathological,
environmental, hormonal, and genetic factors, but a unified molecular basis remains elusive …

In humans, glucocorticoids (GCs) are commonly prescribed because of their anti-
inflammatory and immunosuppressive properties. However, high doses of GCs often lead to …

Synthetic glucocorticoids are clinically used to treat auto-immune and inflammatory disease.
Despite the high efficacy, glucocorticoid treatments causes side effects such as obesity and …

Metabolic crosstalk from skeletal muscle to multiple organs is important for maintaining
homeostasis, and its dysregulation can lead to various diseases. Chronic glucocorticoid …

Glucocorticoids (GCs) play an important role in metabolic adaptation, regulating
carbohydrate-lipid homeostasis and the immune system. Because they also have anti …

Lipid metabolism includes lipogenesis, lipolysis, and cholesterol metabolism and it exerts a
wide range of biological effects. We previously found novel roles of adipocyte oxidative …

Abstract Aim Glucocorticoids (GCs) play a crucial role in energy homeostasis including white
adipose tissue function; however, chronic GC excess is detrimental to mammals' health …

The most common form of hypercortisolism is iatrogenic Cushing's syndrome. Lipodystrophy
and metabolic disorders can result from the use of exogenous glucocorticoids (GC) …