Over the past decade, researchers in the pharmaceutical industry and academia have made
retrospective analyses of successful drug campaigns in order to establish" rules" to guide …

The need for new antibiotic therapies is acute and growing in large part because of the
emergence of drug-resistant pathogens. A vast number of resistance determinants are …

We present an in‐depth analysis of selected CASP15 targets, focusing on their biological
and functional significance. The authors of the structures identify and discuss key protein …

Roughly a third of the world's population is estimated to have latent Mycobacterium
tuberculosis infection, being at risk of develo** active tuberculosis (TB) during their …

Fermentation of Theobroma cacao L. beans is the most critical stage in the production of
cocoa products such as chocolates and its derivatives. There is a limited understanding of …

Shikimate kinase (SK) is an essential enzyme in several pathogenic bacteria and does not
have any counterpart in human cells, thus making it an attractive target for the development …

Capsular polysaccharides are well‐established virulence factors of pathogenic bacteria.
Their biosynthesis and export are regulated within the transmembrane polysaccharide …

Shikimate kinase (SK) and other enzymes in the shikimate pathway are potential targets in
the discovery of antimicrobial agents. In the current study, an ultrafiltration-liquid …

Polyploidy events are believed to be responsible for increasing the size of plant organs and
enhancing tolerance to environmental stresses. Autotetraploid Paulownia australis plants …

Mesorhizobium loti MAFF303099, a microsymbiont of the model legume Lotus japonicus,
possesses a cluster of genes (tts) that encode a type III secretion system (T3SS). In the …