How Droplets Can Accelerate Reactions─ Coacervate Protocells as Catalytic Microcompartments

IBA Smokers, BS Visser, AD Slootbeek… - Accounts of Chemical …, 2024 - ACS Publications
Conspectus Coacervates are droplets formed by liquid–liquid phase separation (LLPS) and
are often used as model protocells–primitive cell-like compartments that could have aided …

Metal–phenolic network composites: from fundamentals to applications

Z Lin, H Liu, JJ Richardson, W Xu, J Chen… - Chemical Society …, 2024 - pubs.rsc.org
Composites with tailored compositions and functions have attracted widespread scientific
and industrial interest. Metal–phenolic networks (MPNs), which are composed of phenolic …

Template-based copying in chemically fuelled dynamic combinatorial libraries

CME Kriebisch, L Burger, O Zozulia, M Stasi… - Nature Chemistry, 2024 - nature.com
One of science's greatest challenges is determining how life can spontaneously emerge
from a mixture of molecules. A complicating factor is that life and its molecules are inherently …

Coacervate droplets for synthetic cells

Z Lin, T Beneyton, JC Baret, N Martin - Small Methods, 2023 - Wiley Online Library
The design and construction of synthetic cells–human‐made microcompartments that mimic
features of living cells–have experienced a real boom in the past decade. While many efforts …

A visible light-activated azo-fluorescent switch for imaging-guided and light-controlled release of antimycotics

Y Huang, X Zeng, X Ma, Z Lin, J Sun, W **ao… - Nature …, 2024 - nature.com
Azo switches are widely employed as essential components in light-responsive systems.
Here, we develop an azo-fluorescent switch that is visible light-responsive and its light …

Recent Progress in Azobenzene‐Based Supramolecular Materials and Applications

M Younis, S Ahmad, A Atiq… - The Chemical …, 2023 - Wiley Online Library
Azobenzene‐containing small molecules and polymers are functional photoswitchable
molecules to form supramolecular nanomaterials for various applications. Recently …

Phase‐Separated Droplets Can Direct the Kinetics of Chemical Reactions Including Polymerization, Self‐Replication and Oscillating Networks

IBA Smokers, BS Visser, WP Lipiński… - …, 2025 - Wiley Online Library
Phase‐separated compartments can localize (bio) chemical reactions and influence their
kinetics. They are believed to play an important role both in extant life in the form of …

Nucleotide-mediated modulation of chemoselective protein functionalization in a liquid-like condensed phase

NK Ettikkan, P Priyanka, RR Mahato… - Communications Chemistry, 2024 - nature.com
Liquid-like protein condensates are ubiquitous in cellular system and are increasingly
recognized for their roles in physiological processes. Condensed phase harbors distinctive …

Random-Sequence DNA Oligomers Make Liquid Crystals: A Case of Collective Ordering in a Superdiverse Environment

S Marni, TP Fraccia, T Bellini - ACS nano, 2024 - ACS Publications
The availability of synthetic, analytical, and predictive tools makes DNA an ideal platform,
not yet considered, to investigate statistical and soft matter physics. Here we report and …

Chemically Triggered Reactive Coacervates Show Life-Like Budding and Membrane Formation

S Koppayithodi, N Singh - Journal of the American Chemical …, 2024 - ACS Publications
Phase-separated coacervates can enhance reaction kinetics and guide multilevel self-
assembly, mimicking early cellular evolution. In this work, we introduce “reactive” complex …