Single-molecule localization microscopy (SMLM) is a relatively new imaging modality,
winning the 2014 Nobel Prize in Chemistry, and considered as one of the key super …

Super-resolution microscopy (SRM) methods have allowed scientists to exceed the
diffraction limit of light, enabling the discovery and investigation of cellular structures at the …

Deep Learning (DL) methods are powerful analytical tools for microscopy and can
outperform conventional image processing pipelines. Despite the enthusiasm and …

Alpha-synuclein is known to bind to small unilamellar vesicles (SUVs) via its N terminus,
which forms an amphipathic alpha-helix upon membrane interaction. Here we show that …

Direct stochastic optical reconstruction microscopy (d STORM) uses conventional
fluorescent probes such as labeled antibodies or chemical tags for subdiffraction resolution …

Photoactivated localization microscopy (PALM) is a powerful approach for investigating
protein organization, yet tools for quantitative, spatial analysis of PALM datasets are largely …

Antigen recognition by the T-cell receptor (TCR) is a hallmark of the adaptive immune
system. When the TCR engages a peptide bound to the restricting major histocompatibility …

TIGIT is an inhibitory receptor expressed on lymphocytes and can inhibit T cells by
preventing CD226 co-stimulation through interactions in cis or through competition of shared …

An interesting concept in the organization of cellular membranes is the proposed existence
of lipid rafts. Membranes of eukaryotic cells organize signal transduction proteins into …

Telomeres, repetitive DNA sequences at chromosome ends, are shielded against the DNA
damage response (DDR) by the shelterin complex. To understand how shelterin protects …