Novel uses of retinal imaging with optical coherence tomography in multiple sclerosis

FC Oertel, HG Zimmermann, AU Brandt… - Expert Review of …, 2019 - Taylor & Francis
ABSTRACT Introduction: Multiple Sclerosis (MS) is the most common chronic autoimmune
neuroinflammatory condition in young adults. It is often accompanied by optic neuritis (ON) …

Detecting neurodegenerative pathology in multiple sclerosis before irreversible brain tissue loss sets in

J Van Schependom, K Guldolf, MB D'hooghe… - Translational …, 2019 - Springer
Background Multiple sclerosis (MS) is a complex chronic inflammatory and degenerative
disorder of the central nervous system. Accelerated brain volume loss, or also termed …

Use of corneal confocal microscopy to detect corneal nerve loss and increased dendritic cells in patients with multiple sclerosis

G Bitirgen, Z Akpinar, RA Malik… - JAMA …, 2017 - jamanetwork.com
Importance Multiple sclerosis (MS) is characterized by demyelination, axonal degeneration,
and inflammation. Corneal confocal microscopy has been used to identify axonal …

[HTML][HTML] Progressive loss of retinal ganglion cells and axons in nonoptic neuritis eyes in multiple sclerosis: a longitudinal optical coherence tomography study

EC Graham, Y You, C Yiannikas, R Garrick… - … & visual science, 2016 - arvojournals.org
Purpose: To examine the rate of retinal ganglion cell (RGC) layer and retinal nerve fiber
layer (RNFL) changes in nonoptic neuritis (NON) eyes of relapsing remitting multiple …

Progressive loss of corneal and retinal nerve fibers in patients with multiple sclerosis: a 2-year follow-up study

G Bitirgen, Z Akpinar, AU Uca… - … Vision Science & …, 2020 - tvst.arvojournals.org
Purpose: To determine longitudinal alterations in corneal nerve fiber morphology, dendritic
cell (DC) density, and retinal nerve fiber layer (RNFL) thickness over 2 years in patients with …

Optical coherence tomography in multiple sclerosis

JS Graves - Seminars in Neurology, 2019 - thieme-connect.com
Optical coherence tomography (OCT) grew out of a convergence of rapid advancements in
femtoseconds optics research and fiber optic commercial technology. The basic concept of …

Retinal degeneration is associated with brain volume reduction and prognosis in radiologically isolated syndrome

A Vural, S Okar, A Kurne, G Sayat-Gürel… - Multiple Sclerosis …, 2020 - journals.sagepub.com
Background: The extent of neurodegeneration in the earliest stages of central nervous
system (CNS) demyelination is not known. Optical coherence tomography (OCT) is a …

Neuroaxonal degeneration in patients with multiple sclerosis: an optical coherence tomography and in vivo corneal confocal microscopy study

V Testa, N De Santis, R Scotto, CE Pastorino… - Cornea, 2020 - journals.lww.com
Purpose: To investigate the effect of multiple sclerosis (MS) on corneal and retinal nerve
fiber by quantifying corneal subbasal nerve fibers and retinal ganglion cells. Methods: A total …

Corneal epithelial dendritic cells in patients with multiple sclerosis: An in vivo confocal microscopy study

V Testa, N De Santis, R Scotto, P Della Giustina… - Journal of Clinical …, 2020 - Elsevier
Purpose To evaluate density and morphology of corneal epithelial dendritic cells (DCs) in
patients with multiple sclerosis (MS) using in vivo confocal microscopy (IVCM). Methods This …

The relationship between optical coherence tomography and magnetic resonance imaging measurements in people with multiple sclerosis: A systematic review and …

O Mirmosayyeb, MY Panah, EM Ghaffary… - Journal of the …, 2025 - Elsevier
Background Several studies show that optical coherence tomography (OCT) metrics have
correlated with cognition, disability, and brain structure in people with multiple sclerosis …