Long non-coding RNAs (lncRNAs) are a diverse class of RNAs that engage in numerous
biological processes across every branch of life. Although initially discovered as mRNA-like …

Discoveries over the past decade portend a paradigm shift in molecular biology. Evidence
suggests that RNA is not only functional as a messenger between DNA and protein but also …

Recently, a new regulatory circuitry has been identified in which RNAs can crosstalk with
each other by competing for shared microRNAs. Such competing endogenous RNAs …

In mammals and other eukaryotes most of the genome is transcribed in a developmentally
regulated manner to produce large numbers of long non-coding RNAs (ncRNAs). Here we …

Transcription, translation and subsequent protein modification represent the transfer of
genetic information from the archival copy of DNA to the short-lived messenger RNA, usually …

Most of the eukaryotic genome is transcribed, yielding a complex network of transcripts that
includes tens of thousands of long noncoding RNAs with little or no protein-coding capacity …

Genome-wide studies have revealed that mammalian genomes are pervasively transcribed.
This has led to the identification and isolation of novel classes of non-coding RNAs …

Recent RNA sequencing studies have revealed that most of the human genome is
transcribed, but very little of the total transcriptomes has the ability to encode proteins. Long …

Recently, a novel class of transcripts, long non-coding RNAs (lncRNAs), is being identified
at a rapid pace. These RNAs have critical roles in diverse biological processes, including …

For 50 years the term 'gene'has been synonymous with regions of the genome encoding
mRNAs that are translated into protein. However, recent genome‐wide studies have shown …