The glymphatic system is a fluid-transport system that accesses all regions of the brain. It
facilitates the exchange of cerebrospinal fluid and interstitial fluid and clears waste from the …

Over the past decade there has been an enormous progress in our understanding of fluid
and solute transport in the central nervous system (CNS). This is due to a number of factors …

Background Despite advances in in vivo imaging and experimental techniques, the nature of
transport mechanisms in the brain remain elusive. Mathematical modelling verified using …

Objective To evaluate human glymphatics and meningeal lymphatics noninvasively.
Methods This prospective study implemented 3‐dimensional (3D) isotropic contrast …

We investigated the effect of mild traumatic brain injury (mTBI) on the glymphatic pathway
using contrast-enhanced magnetic resonance imaging (CE-MRI) and quantified with kinetic …

The glymphatic system functions in the removal of potentially harmful metabolites and
proteins from the brain. Dynamic, contrast-enhanced MRI was used in fully awake rats to …

Objective Impaired glymphatic waste clearance function during brain aging leads to the
accumulation of metabolic waste and neurotoxic proteins (eg, amyloid-β, tau) which …

Perioperative neurocognitive disorder (PND) frequently occurs in the elderly as a severe
postoperative complication and is characterized by a decline in cognitive function that …

BACKGROUND: Blood-brain barrier damage has traditionally been considered to determine
the occurrence and development of poststroke brain edema, a devastating and life …

Background Pathomechanism of secondary degeneration in remote regions after ischemic
stroke has not been totally clarified. Contrast-enhanced MRI with injecting Gd-DTPA in …