[HTML][HTML] Research progress of in-situ gelling ophthalmic drug delivery system
Y Wu, Y Liu, X Li, D Kebebe, B Zhang, J Ren… - Asian journal of …, 2019 - Elsevier
Blindness and vision impairment are the most devastating global health problems resulting
in a substantial economic and social burden. Delivery of drug to particular parts of the …
in a substantial economic and social burden. Delivery of drug to particular parts of the …
[HTML][HTML] Recent advances in nanocarrier-assisted therapeutics delivery systems
S Su, PM Kang - Pharmaceutics, 2020 - mdpi.com
Nanotechnologies have attracted increasing attention in their application in medicine,
especially in the development of new drug delivery systems. With the help of nano-sized …
especially in the development of new drug delivery systems. With the help of nano-sized …
Current insights on antifungal therapy: Novel nanotechnology approaches for drug delivery systems and new drugs from natural sources
The high incidence of fungal infections has become a worrisome public health issue, having
been aggravated by an increase in host predisposition factors. Despite all the drugs …
been aggravated by an increase in host predisposition factors. Despite all the drugs …
Fluconazole-loaded solid lipid nanoparticles topical gel for treatment of pityriasis versicolor: formulation and clinical study
S El-Housiny, MA Shams Eldeen, YA El-Attar… - Drug Delivery, 2018 - Taylor & Francis
Solid lipid nanoparticles (SLNs) are very potential formulations for topical delivery of
antifungal drugs. Hence, the purpose of this research was to formulate the well-known …
antifungal drugs. Hence, the purpose of this research was to formulate the well-known …
In situ gel of triamcinolone acetonide-loaded solid lipid nanoparticles for improved topical ocular delivery: Tear kinetics and ocular disposition studies
Triamcinolone acetonide (TA), an intermediate acting corticosteroid, is used in the treatment
of posterior ocular diseases, such as inflammation, posterior uveitis, and diabetic macular …
of posterior ocular diseases, such as inflammation, posterior uveitis, and diabetic macular …
Solid lipid nanoparticles as promising tool for intraocular tobramycin delivery: Pharmacokinetic studies on rabbits
P Chetoni, S Burgalassi, D Monti, S Tampucci… - European Journal of …, 2016 - Elsevier
Eye drops are widely accepted as formulations for targeting the anterior segment
notwithstanding their limitations in terms of bioavailability. The unique structure of the eye …
notwithstanding their limitations in terms of bioavailability. The unique structure of the eye …
Voriconazole loaded nanostructured lipid carriers based topical delivery system: QbD based designing, characterization, in-vitro and ex-vivo evaluation
T Waghule, VK Rapalli, G Singhvi, P Manchanda… - Journal of drug delivery …, 2019 - Elsevier
Clinical investigation showed that voriconazole exhibits various adverse effects such as
nausea, vomiting, and other gastric disturbances. To overcome these associated side …
nausea, vomiting, and other gastric disturbances. To overcome these associated side …
Improving therapeutic efficacy of voriconazole against fungal keratitis: Thermo-sensitive in situ gels as ophthalmic drug carriers
The aim of this research was to evaluate the potential use of in situ gel formulations for
voriconazole ocular delivery as fungal keratitis treatment. The in situ gelling system was …
voriconazole ocular delivery as fungal keratitis treatment. The in situ gelling system was …
Designing lipid nanoparticles for topical ocular drug delivery
J Alvarez-Trabado, Y Diebold, A Sanchez - International Journal of …, 2017 - Elsevier
Topically-applied dosage forms, such eye drops, are the most used formulations in the
treatment of ocular diseases. Nonetheless, because of the special protection of the eye …
treatment of ocular diseases. Nonetheless, because of the special protection of the eye …
Development and Characterization of PLGA Nanoparticle-Laden Hydrogels for Sustained Ocular Delivery of Norfloxacin in the Treatment of Pseudomonas Keratitis …
Aim Norfloxacin (NFX) has low ocular bioavailability. The current work aimed to develop
NFX-loaded nanoparticle (NP)-laden hydrogels to improve the ocular potential of NFX …
NFX-loaded nanoparticle (NP)-laden hydrogels to improve the ocular potential of NFX …