Cancer evolution: Darwin and beyond
Clinical and laboratory studies over recent decades have established branched evolution as
a feature of cancer. However, while grounded in somatic selection, several lines of evidence …
a feature of cancer. However, while grounded in somatic selection, several lines of evidence …
Properties and application of cell-free DNA as a clinical biomarker
Biomarkers are valuable tools in clinical practice. In 2001, the National Institutes of Health
(NIH) standardized the definition of a biomarker as a characteristic that is objectively …
(NIH) standardized the definition of a biomarker as a characteristic that is objectively …
The provocative roles of platelets in liver disease and cancer
Both platelets and the liver play important roles in the processes of coagulation and innate
immunity. Platelet responses at the site of an injury are rapid; their immediate activation and …
immunity. Platelet responses at the site of an injury are rapid; their immediate activation and …
[HTML][HTML] The provocative roles of platelets in liver disease and cancer
Both platelets and the liver play important roles in the processes of coagulation and innate
immunity. Platelet responses at the site of an injury are rapid; their immediate activation and …
immunity. Platelet responses at the site of an injury are rapid; their immediate activation and …
Liquid biopsy in ovarian cancer
Ovarian cancer is typically diagnosed at an advanced stage and poses a significant
challenge to treatment and recovery. Relapsed ovarian cancer and chemoresistance of …
challenge to treatment and recovery. Relapsed ovarian cancer and chemoresistance of …
Future directions in the use of SAbR for the treatment of oligometastatic cancers
The role of local therapy as a sole therapy or part of a combined approach in treating
metastatic cancer continues to evolve. The most obvious requirements for prudent …
metastatic cancer continues to evolve. The most obvious requirements for prudent …
[HTML][HTML] Circulating tumor DNA in clinical trials for solid tumors: Challenges and current applications
Tumor derived biomarkers including circulating tumor DNA (ctDNA) and/or circulating
tumors cells (CTCs) may be detected and quantified through liquid biopsy (LB). ctDNA …
tumors cells (CTCs) may be detected and quantified through liquid biopsy (LB). ctDNA …
Circulating tumor DNA (ctDNA) application in investigation of cancer: bench to bedside
Now, genomics forms the core of the precision medicine concept. Comprehensive
investigations of tumor genomes have made it possible to characterize tumors at the …
investigations of tumor genomes have made it possible to characterize tumors at the …
Ready-to-use nanopore platform for the detection of any DNA/RNA oligo at attomole range using an Osmium tagged complementary probe
ASW Kang, JG Bernasconi, W Jack, A Kanavarioti - Scientific reports, 2020 - nature.com
Nanopores can serve as single molecule sensors. We exploited the MinION, a portable
nanopore device from Oxford Nanopore Technologies, and repurposed it to detect any …
nanopore device from Oxford Nanopore Technologies, and repurposed it to detect any …
An overview: genetic tumor markers for early detection and current gene therapy strategies
R Quraish, T Hirahata, A Quraish… - Cancer …, 2023 - journals.sagepub.com
Genomic instability is considered a fundamental factor involved in any neoplastic disease.
Consequently, the genetically unstable cells contribute to intratumoral genetic heterogeneity …
Consequently, the genetically unstable cells contribute to intratumoral genetic heterogeneity …