Neurons that synthesize and release 5-hydroxytryptamine (5-HT; serotonin) express a core
set of genes that establish and maintain this neurotransmitter phenotype and distinguish …

The continuing fascination with serotonin (5‐hydroxytryptamine, 5‐HT) as a nervous system
chemical messenger began with its discovery in the brains of mammals in 1953. Among the …

Serotonin neurons of the dorsal and median raphe nuclei (DR, MR) collectively innervate
the entire forebrain and midbrain, modulating diverse physiology and behavior. To gain a …

INTRODUCTION Co** with negative experience is essential for survival. Animals must
quickly recognize a harmful situation, produce an adequate response, and learn its context …

Exposure to stressors has profound effects on sleep that have been linked to serotonin (5-
HT) neurons of the dorsal raphe nucleus (DR). However, the DR also comprises …

Hippocampus receives dense serotonergic input specifically from raphe nuclei. However,
what information is carried by this input and its impact on behavior has not been fully …

The dorsal raphe nucleus (DR) and median raphe nucleus (MR) contain populations of
glutamatergic and GABAergic neurons that regulate diverse behavioral functions. However …

The lateral hypothalamus (LH), together with multiple neuromodulatory systems of the brain,
such as the dorsal raphe nucleus (DR), is implicated in arousal, yet interactions between …

A role for the brain's serotoninergic (5HT) system in the regulation of sleep and wakefulness
has been long suggested. Yet, previous studies employing pharmacological, lesion and …

Brainstem median raphe (MR) neurons expressing the serotonergic regulator gene Pet1
send collateralized projections to forebrain regions to modulate affective, memory-related …