Potassium channels are transmembrane proteins that selectively facilitate the flow of
potassium ions down an electrochemical gradient. These molecules have been studied in …

The identification of neurological symptoms caused by vitamin A deficiency pointed to a
critical, early developmental role of vitamin A and its metabolite, retinoic acid (RA). The …

Endocrine tumors such as aldosterone-producing adrenal adenomas (APAs), a cause of
severe hypertension, feature constitutive hormone production and unrestrained cell …

Calmodulin (CaM) is a ubiquitous Ca 2+ receptor protein mediating a large number of
signaling processes in all eukaryotic cells. CaM plays a central role in regulating a myriad of …

Increases in cytosolic free Ca2+ ([Ca2+] i) represent a ubiquitous signalling mechanism that
controls a variety of cellular processes, including proliferation, metabolism and gene …

Large segmental bone loss and bone resection due to trauma and/or the presence of tumors
and cysts often results in a delay in healing or non-union. Currently, the bone autograft is the …

In the cardiomyocyte, CaMKII has been identified as a nodal influencer of excitation–
contraction and also excitation–transcription coupling. Its activity can be regulated in …

Cell proliferation is orchestrated through diverse proteins related to calcium (Ca 2+)
signaling inside the cell. Cellular Ca 2+ influx that occurs first by various mechanisms at the …

Molecular recognition by proteins is fundamental to almost every biological process,
particularly the protein associations underlying cellular signal transduction. Understanding …

Introduction: The beneficial effects of oleic acid in cancer processes can no longer be
doubted, but little is known about the mechanisms of action behind this phenomenon. Aim …