Neurodegenerative diseases pose a substantial socioeconomic burden on society.
Unfortunately, the aging world population and lack of effective cures foreshadow a negative …

Few proteins have come under such intense scrutiny as superoxide dismutase-1 (SOD1).
For almost a century, scientists have dissected its form, function and then later its …

Insoluble protein aggregates with fibrillar morphology called amyloids and β-barrel proteins
both share a β-sheet-rich structure. Correctly folded β-barrel proteins can not only function in …

Cu/Zn superoxide dismutase‐1 (SOD 1) mutations are causative for a subset of amyotrophic
lateral sclerosis (ALS) cases. These mutations lead to structural instability, aggregation and …

Amyloids have special structural properties and are involved in many aspects of biological
function. In particular, amyloids are the cause or hallmarks of a group of notorious and …

Sample preparation for solid‐state NMR of soluble proteins is all but a trivial
accomplishment and often represents the factor that determines the success of the …

Over the years number of books, comprehensive reviews and biennial reports have been
published on the study of oriented molecules using NMR spectroscopy. The present …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterised by the
rapid and progressive degeneration of upper and lower motor neurons in the spinal cord …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease affecting the upper and
lower motor neurons causing muscle atrophy and paralysis followed by death. Aggregates …

136 136 5.1. 2 Spins in a magnetic field 137 5.1. 3 The chemical shift 138 5.1. 4
Radiofrequency pulses and Fourier transform 138 5.1. 5 Vectorial description, the rotating …