Strategies for targeted gene delivery using lipid nanoparticles and cell-derived nanovesicles

D Lee, S Amirthalingam, C Lee, AK Rajendran… - Nanoscale …, 2023 - pubs.rsc.org
Gene therapy is a promising approach for the treatment of many diseases. However, the
effective delivery of the cargo without degradation in vivo is one of the major hurdles. With …

Locust bean gum hydrogel containing Indole-3-carbinol nanocapsules has prolonged cutaneous anti-inflammatory action

LM Giuliani, BF Osmari, C Camponogara… - Journal of Drug Delivery …, 2023 - Elsevier
This study aimed to prepare a locust bean gum-based hydrogel containing indole-3-carbinol
(I3C) Eudragit® RS 100 nanocapsule for treating skin inflammatory disorders. The interfacial …

Ethosomal gel for topical administration of dimethyl fumarate in the treatment of HSV-1 infections

M Sicurella, W Pula, K Musiał… - International Journal of …, 2023 - mdpi.com
The infections caused by the HSV-1 virus induce lesions on the lips, mouth, face, and eye. In
this study, an ethosome gel loaded with dimethyl fumarate was investigated as a possible …

Bioactive-Loaded Hydrogels Based on Bacterial Nanocellulose, Chitosan, and Poloxamer for Rebalancing Vaginal Microbiota

A Moraru, ȘO Dima, N Tritean, EI Oprița… - Pharmaceuticals, 2023 - mdpi.com
Biocompatible drug-delivery systems for soft tissue applications are of high interest for the
medical and pharmaceutical fields. The subject of this research is the development of …

[PDF][PDF] A narrative review on Epidermal Growth Factor (EGF) intralesional infiltrations for diabetic complex wounds: The rational of an innovative delivery route

J Berlanga-Acosta, MJ Fernandez, H Santana… - Vasc. Dis …, 2022 - researchgate.net
Diabetes mellitus remains as a pandemic disease, associated to progressive and
irreversible complications including lower extremity ulcerations, derived from a …

Efficiency Improvement of Lipid Based Gene Delivery Platform for mRNA, pDNA, siRNA Delivery

이동엽 - 2024 - s-space.snu.ac.kr
Lipid nanoparticles (LNPs) containing ionizable cationic lipids represent the most clinically
advanced platform for gene delivery owing to favorable safety and efficacy. Prior studies in …