A Self‐Catalytic NO/O2 Gas‐Releasing Nanozyme for Radiotherapy Sensitization through Vascular Normalization and Hypoxia Relief

S Wang, M Cheng, S Wang, W Jiang, F Yang… - Advanced …, 2024 - Wiley Online Library
Radiotherapy (RT), essential for treating various cancers, faces challenges from tumor
hypoxia, which induces radioresistance. A tumor‐targeted “prosthetic‐Arginine” …

Photodynamic therapy based on metal-organic framework in cancer treatment: A comprehensive review of integration strategies for synergistic combination therapies

M Karbasi, M Varzandeh, M Karbasi… - Nano-Structures & Nano …, 2024 - Elsevier
Recent advancements in cancer therapy have prompted the exploration of innovative and
synergistic treatment modalities to minimize side effects and enhance efficacy …

Inorganic nanoparticles as radiosensitizers for cancer treatment

B Babu, SA Stoltz, A Mittal, S Pawar, E Kolanthai… - Nanomaterials, 2023 - mdpi.com
Nanotechnology has expanded what can be achieved in our approach to cancer treatment.
The ability to produce and engineer functional nanoparticle formulations to elicit higher …

Current paradigms in employing self-assembled structures: Drug delivery implications with improved therapeutic potential

A Sharma, M Singh, V Sharma, A Vashishth… - Colloids and Surfaces B …, 2024 - Elsevier
Recent efforts have focused on develo** improved drug delivery systems with enhanced
therapeutic efficacy and minimal side effects. Micelles, self-assembled from amphiphilic …

Murine breast cancer radiosensitization using oxygen microbubbles and metformin: vessels are the key

A Drzał, G Dziurman, P Hoła, J Lechowski… - International Journal of …, 2023 - mdpi.com
Radiotherapy is a cornerstone of cancer treatment, but tumor hypoxia and resistance to
radiation remain significant challenges. Vascular normalization has emerged as a strategy …

Gd-GQDs as nanotheranostic platform for the treatment of HPV-positive oropharyngeal cancer

M Ahmadi Kamalabadi, H Ostadebrahimi, F Koosha… - Medical Oncology, 2024 - Springer
In this study, we developed new gadolinium-graphene quantum dot nanoparticles (Gd-
GQDs) as a theranostic platform for magnetic resonance imaging and improved the …

Targeted cancer treatment using folate-conjugated sponge-like ZIF-8 nanoparticles: a review

MA Oryani, S Nosrati, H Javid, A Mehri… - Naunyn-Schmiedeberg's …, 2024 - Springer
Abstract ZIF-8 (zeolitic imidazolate framework-8) is a potential drug delivery system because
of its unique properties, which include a large surface area, a large pore capacity, a large …

Clonogenic assay and computational modeling using real cell images to study physical enhancement and cellular sensitization induced by metal nanoparticles under …

RH Millares, C Bae, SJ Kim, T Kim, SY Park, K Lee… - Nanoscale, 2024 - pubs.rsc.org
This study was initiated due to the physically unexplainable tumor controls resulting from
metal nanoparticle (MNP) experiments even under MV X-ray irradiation. A more accurate …

Au-based conjugated microporous polymers for combined photodynamic and radiation therapy in cancer treatment

X Pan, S Cui, S Fan, C Cao, Y Jiao, Y Fu… - Materials Chemistry …, 2024 - pubs.rsc.org
Radiotherapy (RT) is a cornerstone of cancer treatment, and the radiation dose is the key
factor determining its lethality. However, achieving ideal therapeutic effects requires …

Biodegradable hafnium-doped CaCO3 nanoparticles as a dual-modality radiosensitizer for cancer radiotherapy

MH Chen, XH Zeng, YT Shu, HK Liang, CY Chen… - …, 2024 - Taylor & Francis
Aim: Radiotherapy employs high-energy ionizing radiation to inflict DNA damage on cancer
cells, thereby causing their demise. However, this procedure can inadvertently harm healthy …