Over the past decade, single-cell genomics technologies have allowed scalable profiling of
cell-type-specific features, which has substantially increased our ability to study cellular …

The role of genetic testing in the domain of neurodevelopmental and psychiatric disorders
(NPDs) is gradually changing from providing etiological explanation for the presence of NPD …

Abstract Background The 22q11. 2 deletion syndrome (22qDel) is a genetic copy number
variant that strongly increases risk for schizophrenia and other neurodevelopmental …

Depression-anxiety comorbidity is commonly attributed to the occurrence of specific
symptoms bridging the two disorders. However, the significant heterogeneity of most …

Background There is little consensus and controversial evidence on anatomical alterations
in the brains of people with autism spectrum disorder (ASD), due in part to the large …

There is widespread overlap across major psychiatric disorders, and this is the case at
different levels of observations, from genetic variants to brain structures and function and to …

A common anatomical core has been described for psychiatric disorders, consisting of the
dorsal anterior cingulate cortex (dACC) and anterior insula, processing uncertainty. A …

Traits often do not evolve in isolation or vary independently of other traits. Instead, they can
be affected by covariation, both within and across species. However, the importance of …

Background Neuropsychiatric and neurodegenerative disorders involve diverse changes in
brain functional connectivity. As an alternative to approaches that search for specific mosaic …

A broad range of neuropsychiatric disorders are associated with alterations in macroscale
brain circuitry and connectivity. Identifying consistent brain patterns underlying these …