Cation-chloride cotransporters and neuronal function

P Blaesse, MS Airaksinen, C Rivera, K Kaila - Neuron, 2009 - cell.com
Recent years have witnessed a steep increase in studies on the diverse roles of neuronal
cation-chloride cotransporters (CCCs). The versatility of CCC gene transcription …

The GABA nervous system in C. elegans

K Schuske, AA Beg, EM Jorgensen - Trends in neurosciences, 2004 - cell.com
GABA neurotransmission requires a specialized set of proteins to synthesize, transport or
respond to GABA. This article reviews results from a genetic strategy in the nematode …

Uptake of nanopolystyrene particles induces distinct metabolic profiles and toxic effects in Caenorhabditis elegans

HM Kim, DK Lee, NP Long, SW Kwon, JH Park - Environmental pollution, 2019 - Elsevier
Nanoplastics are widely used in modern life, for example, in cosmetics and daily use
products, and are attracting concern due to their potential toxic effects on environments. In …

Mitochondria localize to injured axons to support regeneration

SM Han, HS Baig, M Hammarlund - Neuron, 2016 - cell.com
Axon regeneration is essential to restore the nervous system after axon injury. However, the
neuronal cell biology that underlies axon regeneration is incompletely understood. Here we …

UNC-13 is required for synaptic vesicle fusion in C. elegans

JE Richmond, WS Davis, EM Jorgensen - Nature neuroscience, 1999 - nature.com
We analyzed the synaptic physiology of unc-13 mutants in the nematode C. elegans.
Mutants of unc-13 had normal nervous system architecture, and the densities of synapses …

Photoaged microplastics induce neurotoxicity associated with damage to serotonergic, glutamatergic, dopaminergic, and GABAergic neuronal systems in …

Y Yu, S Tan, D **e, H Li, H Chen, Y Dang… - Science of The Total …, 2023 - Elsevier
Microplastics (MPs) are ubiquitous environmental contaminants that cause neurotoxicity in
various organisms. MPs are typically affected by light irradiation and undergo photoaging …

GABAergic signaling between enteric neurons and intestinal smooth muscle promotes innate immunity and gut defense in Caenorhabditis elegans

J Liu, P Zhang, Z Zheng, MI Afridi, S Zhang, Z Wan… - Immunity, 2023 - cell.com
The nervous system is critical for intestinal homeostasis and function, but questions remain
regarding its impact on gut immune defense. By screening the major neurotransmitters of C …

Proprioceptive coupling within motor neurons drives C. elegans forward locomotion

Q Wen, MD Po, E Hulme, S Chen, X Liu, SW Kwok… - neuron, 2012 - cell.com
Locomotion requires coordinated motor activity throughout an animal's body. In both
vertebrates and invertebrates, chains of coupled central pattern generators (CPGs) are …

Neurodegeneration and defective neurotransmission in a Caenorhabditis elegans model of tauopathy

BC Kraemer, B Zhang, JB Leverenz… - Proceedings of the …, 2003 - National Acad Sciences
Frontotemporal dementia with parkinsonism chromosome 17 type (FTDP-17) is caused by
mutations in MAPT, the gene encoding tau. FTDP-17 begins with executive function deficits …

A central role of the BK potassium channel in behavioral responses to ethanol in C. elegans

AG Davies, JT Pierce-Shimomura, H Kim… - Cell, 2003 - cell.com
The activities of many neuronal proteins are modulated by ethanol, but the fundamental
mechanisms underlying behavioral effects of ethanol remain unclear. To identify …